{"type":"trials","record":{"id":41390,"source_id":"clinicaltrials-gov","external_id":"NCT07235527","title":"Real-Life Clinical Outcomes of Aflibercept Biosimilar MY-1701P in the Treatment of Exudative Age-Related Macular Degeneration","brief_summary":"In this study, patients receiving Eylea treatment will be treated with Yesafili, a biosimilar molecule, and routine examination results will be noted.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Saglik Bilimleri Universitesi","enrollment":54,"countries":["Turkey (Türkiye)"],"start_date":"2025-11-20","completion_date":"2026-08-30","last_update_date":"2026-09-01","source_url":"https://clinicaltrials.gov/study/NCT07235527","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"45 Years to 90 Years","comparator":null,"organization":"Saglik Bilimleri Universitesi","interventions":["Aflibercept biosimilar (MY-1701P)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Best-Corrected Visual Acuity (BCVA) and Central Macular Thickness After MY-1701P Injection — Baseline to Mont…","Effect of MY-1701P on Pigment Epithelial Detachment, Neovascularization Size, and Treatment Interval Adjustment — Basel…"],"design_description":null,"source_has_results":false},"controlled_terms":["Age Related Macular Degeneration","Exudative Age-Related Macular Degeneration","Anti Vascular Endothelial Growth Factor","Aflibercept biosimilar (MY-1701P)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct07235527","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-11-20 to 2026-08-30","comparator":null,"confidence":"structured-source","population":"ALL · 45 Years to 90 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.804Z","intervention":["Aflibercept biosimilar (MY-1701P)"],"participants":54,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Best-Corrected Visual Acuity (BCVA) and Central Macular Thickness After MY-1701P Injection — Baseline to Mont…","Effect of MY-1701P on Pigment Epithelial Detachment, Neovascularization Size, and Treatment Interval Adjustment — Basel…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41390","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}