{"type":"trials","record":{"id":41463,"source_id":"clinicaltrials-gov","external_id":"NCT02725762","title":"Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration","brief_summary":"The purpose of this research study is to determine if photobiomodulation is an effective treatment of Dry Age-Related Macular Degeneration (AMD) and vision loss associated with the disease.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"LumiThera, Inc.","enrollment":30,"countries":["Canada"],"start_date":"2016-03-01","completion_date":"2018-07-01","last_update_date":"2026-07-13","source_url":"https://clinicaltrials.gov/study/NCT02725762","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"LIGHTSITE1","age_range":"50 Years","comparator":null,"organization":"LumiThera, Inc.","interventions":["LT-300 Active (PBM)","LT-300 Inactive (Sham)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Visual Acuity changes from baseline to month 12. — Through study completion, an average of one year.","Contrast Sensitivity — Through study completion, an average of one year.","Optical Coherence Tomography (OCT) — Through study completion, an average of one year."],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE","source_has_results":false},"controlled_terms":["Age Related Macular Degeneration","LT-300 Active (PBM)","LT-300 Inactive (Sham)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct02725762","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-03-01 to 2018-07-01","comparator":null,"confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.817Z","intervention":["LT-300 Active (PBM)","LT-300 Inactive (Sham)"],"participants":30,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Visual Acuity changes from baseline to month 12. — Through study completion, an average of one year.","Contrast Sensitivity — Through study completion, an average of one year.","Optical Coherence Tomography (OCT) — Through study completion, an average of one year."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41463","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}