{"type":"trials","record":{"id":41554,"source_id":"clinicaltrials-gov","external_id":"NCT07556406","title":"Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study","brief_summary":"This study is being conducted to assess two imaging methods-central microperimetry and radial OCT (Optical Coherence Tomography)-in patients with Geographic Atrophy (GA) or those who are at risk of developing this condition. The study team is trying to determine whether these methods can provide more accurate measurements of GA progression toward the foveal center, the central part of the retina responsible for your sharpest, most detailed vision.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"University of California, San Francisco","enrollment":80,"countries":["United States"],"start_date":"2025-06-11","completion_date":"2027-06-11","last_update_date":"2026-04-29","source_url":"https://clinicaltrials.gov/study/NCT07556406","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"CORE-GA","age_range":"55 Years","comparator":null,"organization":"University of California, San Francisco","interventions":["Optical coherence tomography","Microperimetry"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Geographic atrophy progression rate — 1 year","Longitudinal progression of macular sensitivity over time — 1 year"],"design_description":null,"source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","Geographic Atrophy","Optical coherence tomography","Microperimetry"],"relevance_confidence":62,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct07556406","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-06-11 to 2027-06-11","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.832Z","intervention":["Optical coherence tomography","Microperimetry"],"participants":80,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Geographic atrophy progression rate — 1 year","Longitudinal progression of macular sensitivity over time — 1 year"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: aging.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["controlled terminology","abstract context","study type"],"relevance_score":62,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41554","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}