{"type":"trials","record":{"id":41577,"source_id":"clinicaltrials-gov","external_id":"NCT03333954","title":"Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular Degeneration","brief_summary":"In this study, the principle functionality of the device will be tested in humans for the first time. The study will evaluate the extent to which patients with atrophic dry age related macular degeneration (AMD) have evoked light perception using the implant.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Science Corporation","enrollment":5,"countries":["France"],"start_date":"2017-11-06","completion_date":"2024-12-12","last_update_date":"2026-04-02","source_url":"https://clinicaltrials.gov/study/NCT03333954","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"PRIMA FS","age_range":"60 Years","comparator":null,"organization":"Science Corporation","interventions":["PRIMA Bionic Vision System"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Elicitation of perception — 6 months after implantation","Elicitation of perception — 6 weeks after implantation","Elicitation of perception — 3 months after implantation","Elicitation of perception — 12 months after implantation","Elicitation of perception — 18 months after implantation","Elicitation of perception — 24 months after implantation","Elicitation of perception — 36 months after implantation","Visual Acuity — 18, 24 and 36 months after implantation if applicable","Letter Visual Acuity — 48, 60 and 72 month after implantation","Quality of Live measured by IVI — 48, 60 and 72 month after implantation"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Dry Age-related Macular Degeneration","PRIMA Bionic Vision System"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct03333954","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2017-11-06 to 2024-12-12","comparator":null,"confidence":"structured-source","population":"ALL · 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.836Z","intervention":["PRIMA Bionic Vision System"],"participants":5,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Elicitation of perception — 6 months after implantation","Elicitation of perception — 6 weeks after implantation","Elicitation of perception — 3 months after implantation","Elicitation of perception — 12 months after implantation","Elicitation of perception — 18 months after implantation","Elicitation of perception — 24 months after implantation","Elicitation of perception — 36 months after implantation","Visual Acuity — 18, 24 and 36 months after implantation if applicable","Letter Visual Acuity — 48, 60 and 72 month after implantation","Quality of Live measured by IVI — 48, 60 and 72 month after implantation"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41577","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}