{"type":"trials","record":{"id":41587,"source_id":"clinicaltrials-gov","external_id":"NCT05913063","title":"Direct Discrimination of Quantum States by the Human Eye","brief_summary":"Age-related macular degeneration (AMD), is a debilitating eye disease that causes a loss of central vision. The prevalence of AMD increases exponentially with age and causes a significant impact through both medical expenses and the social and economic costs associated with vision loss. AMD is the global leading cause of blindness among people over the age of 60. Detection of this eye disease at early stages coupled with prompt treatment can prevent vision loss; however, modern diagnosis methods are ineffective at diagnosis of AMD before vision loss occurs. While a range of available treatment options has been effective at slowing vision loss due to AMD, no treatment exists which can recover lost vision. The investigators propose to apply tools developed in quantum information science to diagnose AMD before vision has been affected, drastically improving health outcomes for patients with AMD.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Centre for Eye and Vision Research","enrollment":50,"countries":["Hong Kong"],"start_date":"2023-06-26","completion_date":"2029-10-01","last_update_date":"2026-03-18","source_url":"https://clinicaltrials.gov/study/NCT05913063","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"Centre for Eye and Vision Research","interventions":["Structured Light Imaging Microscopy"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Perception of the structured light — Approximately 10 minutes, Screening and Training day (Session 1)","Radius of the radial retinal polarizer — Approximately 30 minutes, on the completion of the study (Session 6)","Thickness of retina and retinal layers — Approximately 10 minutes, Screening and Training day (Session 1)","Contrast sensitivity — Approximately 5 minutes, Screening and Training day (Session 1)","Fundus photography — Approximately 5 minutes, Screening and Training day (Session 1)","Ocular biometry measurement — Approximately 5 minutes, Screening and Training day (Session 1)","Macular pigment optical density measurement — Approximately 10 minutes, Screening and Training day (Sessions 1 and 2)"],"design_description":"NA · SINGLE GROUP · DIAGNOSTIC · NONE","source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","Structured Light Imaging Microscopy"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05913063","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-06-26 to 2029-10-01","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.837Z","intervention":["Structured Light Imaging Microscopy"],"participants":50,"study_design":"NA · SINGLE GROUP · DIAGNOSTIC · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Perception of the structured light — Approximately 10 minutes, Screening and Training day (Session 1)","Radius of the radial retinal polarizer — Approximately 30 minutes, on the completion of the study (Session 6)","Thickness of retina and retinal layers — Approximately 10 minutes, Screening and Training day (Session 1)","Contrast sensitivity — Approximately 5 minutes, Screening and Training day (Session 1)","Fundus photography — Approximately 5 minutes, Screening and Training day (Session 1)","Ocular biometry measurement — Approximately 5 minutes, Screening and Training day (Session 1)","Macular pigment optical density measurement — Approximately 10 minutes, Screening and Training day (Sessions 1 and 2)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41587","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}