{"type":"trials","record":{"id":41651,"source_id":"clinicaltrials-gov","external_id":"NCT05465252","title":"Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression","brief_summary":"This randomized, double-blind, placebo-controlled study aims to evaluate the effect of krill oil supplementation in patients with dry age-related macular degeneration (AMD). Participants will receive 4 capsules of krill oil or placebo daily for a period of 3 months. Outcomes will be evaluated after 3-month treatment to assess differences between the two study groups.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","enrollment":24,"countries":["China"],"start_date":"2025-10-17","completion_date":"2026-05-01","last_update_date":"2026-01-02","source_url":"https://clinicaltrials.gov/study/NCT05465252","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"OMEGA-AMD","age_range":"50 Years to 85 Years","comparator":"olive oil","organization":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","interventions":["Krill Oil","Olive Oil"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Macular Drusen Volume — From enrollment to the end of follow-up at 3 months.","Change in Maximum Macular Drusen Height — From enrollment to the end of follow-up at 3 months.","Change in Best-Corrected Visual Acuity — From enrollment to the end of follow-up at 3 months.","Change in Self-Reported Visual Function — From enrollment to the end of follow-up at 3 months."],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","Krill Oil","Olive Oil"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05465252","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-10-17 to 2026-05-01","comparator":"olive oil","confidence":"structured-source","population":"ALL · 50 Years to 85 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.847Z","intervention":["Krill Oil","Olive Oil"],"participants":24,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Macular Drusen Volume — From enrollment to the end of follow-up at 3 months.","Change in Maximum Macular Drusen Height — From enrollment to the end of follow-up at 3 months.","Change in Best-Corrected Visual Acuity — From enrollment to the end of follow-up at 3 months.","Change in Self-Reported Visual Function — From enrollment to the end of follow-up at 3 months."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41651","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}