{"type":"trials","record":{"id":41782,"source_id":"clinicaltrials-gov","external_id":"NCT05675150","title":"Expressive Arts-based Intervention for Adults With Age-related Visual Impairment","brief_summary":"Age-related Macular Degeneration (AMD) is an age-related eye disease resulting in vision loss. Persons with AMD not only experience a gradual loss of ability in independent living, but also profound impairment in psychosocial well-being.The multimodal, expressive arts-based intervention (EXABI) that emphasizes imagination and creativity can be an engaging, enjoyable, and safe process of empowerment. This study aims to investigate the effectiveness and process of an expressive arts-based intervention in enhancing psychosocial wellness and adjustment to gradual vision loss of persons with AMD. This current study will adopt a 2-arm randomized controlled design with treatment-as-usual control. Upon screening for inclusion exclusion criteria, baseline data will be collected; and eligible participants will be randomized into either an 8-week Expressive Arts-based intervention group or Treatment-As-Usual control group.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"The University of Hong Kong","enrollment":154,"countries":["Hong Kong"],"start_date":"2023-05-01","completion_date":"2025-12-31","last_update_date":"2025-05-15","source_url":"https://clinicaltrials.gov/study/NCT05675150","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"50 Years to 80 Years","comparator":"Wait-list control","organization":"The University of Hong Kong","interventions":["Expressive Arts-Based Intervention"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change of Baseline Psychosocial Adaptation Questionnaire for visual impairment level at 2 months, 5 months, and 8 month…","Change of Baseline Vision-related Quality of Life level at 2 months, 5 months, and 8 months — Baseline, post-interventi…","Change of Baseline Anxiety level at 2 months, 5 months, and 8 months — Baseline, post-intervention (Month 2), 3-month p…","Change of Baseline Depression level at 2 months, 5 months, and 8 months — Baseline, post-intervention (Month 2), 3-mont…","Change of Baseline Resilience level at 2 months, 5 months and 8 months — Baseline, post-intervention (Month 2), 3-month…","Change of Baseline Perceived Social Support level at 2 months, 5 months and 8 months — Baseline, post-intervention (Mon…","Change of Baseline Imagination level at 2 months, 5 months, and 8 months — Baseline, post-intervention (Month 2), 3-mon…"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","Expressive Arts-Based Intervention"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05675150","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-05-01 to 2025-12-31","comparator":"Wait-list control","confidence":"structured-source","population":"ALL · 50 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.870Z","intervention":["Expressive Arts-Based Intervention"],"participants":154,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change of Baseline Psychosocial Adaptation Questionnaire for visual impairment level at 2 months, 5 months, and 8 month…","Change of Baseline Vision-related Quality of Life level at 2 months, 5 months, and 8 months — Baseline, post-interventi…","Change of Baseline Anxiety level at 2 months, 5 months, and 8 months — Baseline, post-intervention (Month 2), 3-month p…","Change of Baseline Depression level at 2 months, 5 months, and 8 months — Baseline, post-intervention (Month 2), 3-mont…","Change of Baseline Resilience level at 2 months, 5 months and 8 months — Baseline, post-intervention (Month 2), 3-month…","Change of Baseline Perceived Social Support level at 2 months, 5 months and 8 months — Baseline, post-intervention (Mon…","Change of Baseline Imagination level at 2 months, 5 months, and 8 months — Baseline, post-intervention (Month 2), 3-mon…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41782","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}