{"type":"trials","record":{"id":41861,"source_id":"clinicaltrials-gov","external_id":"NCT06817915","title":"This Project At LMU Looks At How Using AI 2nd Opinion Report to Analyze Retinal Eye Scans Impact Doctors' Decisions About Treatment for Patients with a Specific Eye Disease (nAMD)","brief_summary":"This is a research plan from the University of Munich (LMU) that aims to study how the use of AI reports can impact ophthalmologists' decisions regarding treatment for patients with neovascular age-related macular degeneration (nAMD). This disease is a leading cause of vision loss, and while anti-VEGF treatments are effective, they require careful monitoring and retreatment decisions to maximize benefits. The study will involve up to 1000 ophthalmologists with varying levels of expertise. These ophthalmologists will review SD-OCT scans and make treatment decisions before and after reviewing AI-generated reports. The primary objective is to compare these decisions and see how the AI reports influence them. Secondary objectives include assessing the accuracy and safety of the AI reports.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Johannes Schiefelbein","enrollment":100,"countries":["Germany"],"start_date":"2025-01-30","completion_date":"2026-01-30","last_update_date":"2025-02-10","source_url":"https://clinicaltrials.gov/study/NCT06817915","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"LMU ASSIST","age_range":"18 Years","comparator":null,"organization":"LMU Klinikum","interventions":["AI assisted assessment of SD-OCT scans"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Ophthalmologist's Treatment Decision — There is only one survey filled out by the participant. In this survey, only one…","Performance Accuracy — There is only one survey filled out by the participant. In this survey, only one time point when…","Safety prediciton assessment — There is only one survey filled out by the participant. In this survey, only one time po…","Exploratory AI-CDS report Impact on Decision Making — There is only one survey filled out by the participant. In this s…"],"design_description":"NA · SINGLE GROUP · BASIC SCIENCE · NONE","source_has_results":false},"controlled_terms":["Neovascular Age-Related Macular Degeneration (nAMD)","AI assisted assessment of SD-OCT scans"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct06817915","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-01-30 to 2026-01-30","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.882Z","intervention":["AI assisted assessment of SD-OCT scans"],"participants":100,"study_design":"NA · SINGLE GROUP · BASIC SCIENCE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Ophthalmologist's Treatment Decision — There is only one survey filled out by the participant. In this survey, only one…","Performance Accuracy — There is only one survey filled out by the participant. In this survey, only one time point when…","Safety prediciton assessment — There is only one survey filled out by the participant. In this survey, only one time po…","Exploratory AI-CDS report Impact on Decision Making — There is only one survey filled out by the participant. In this s…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41861","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}