{"type":"trials","record":{"id":41867,"source_id":"clinicaltrials-gov","external_id":"NCT05991986","title":"Preparation of Patient Autologous Induced Pluripotent Stem Cell-derived Retinal Cells for AMD","brief_summary":"This project intends to collect participant somatic cells to prepare autologous induced pluripotent stem cell-derived retinal cells for future cell therapy of age-related macular degeneration patient.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Zhongshan Ophthalmic Center, Sun Yat-sen University","enrollment":10,"countries":[],"start_date":"2025-08-01","completion_date":"2026-07-31","last_update_date":"2025-01-28","source_url":"https://clinicaltrials.gov/study/NCT05991986","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"55 Years to 80 Years","comparator":null,"organization":"Zhongshan Ophthalmic Center, Sun Yat-sen University","interventions":["somatic cell collection"],"registry_source":"ClinicalTrials.gov","outcome_measures":["somatic cell collection — 2023.8.1~2026.7.31"],"design_description":null,"source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","somatic cell collection"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05991986","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-08-01 to 2026-07-31","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.883Z","intervention":["somatic cell collection"],"participants":10,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["somatic cell collection — 2023.8.1~2026.7.31"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41867","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}