{"type":"trials","record":{"id":41875,"source_id":"clinicaltrials-gov","external_id":"NCT06375239","title":"Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration","brief_summary":"The Vision Research and Assessment Institute (VRAI) was established with the purpose of serving as a testing facility for efficacy endpoints for patients with Low Vision. The mission of the VRAI is to enable the highest quality, standardized efficacy testing of patients with visual impairment. The VRAI facilitates the development and refinement of existing endpoints specifically for testing patients with Low Vision.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Ray Therapeutics, Inc.","enrollment":120,"countries":["United States"],"start_date":"2024-04-05","completion_date":"2026-04-30","last_update_date":"2025-01-08","source_url":"https://clinicaltrials.gov/study/NCT06375239","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"Ray Therapeutics, Inc.","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Operational feasibility of testing moderate to profound vision impaired patients with various retinal dystrophies on a…","To quantify patient-based measurement properties of each test modality (for the purposes of endpoint qualification) — 2…","To quantify assessor-based measurement properties of each test modality (for the purposes of endpoint qualification) —…"],"design_description":null,"source_has_results":false},"controlled_terms":["Retinitis Pigmentosa","Choroideremia","Stargardt Macular Dystrophy","Stargardt Disease","Geographic Atrophy from Age-related Macular Degeneration","X-lined Retinoschisis","Retinal Dystrophies"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct06375239","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-04-05 to 2026-04-30","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.885Z","intervention":[],"participants":120,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Operational feasibility of testing moderate to profound vision impaired patients with various retinal dystrophies on a…","To quantify patient-based measurement properties of each test modality (for the purposes of endpoint qualification) — 2…","To quantify assessor-based measurement properties of each test modality (for the purposes of endpoint qualification) —…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41875","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}