{"type":"trials","record":{"id":41970,"source_id":"clinicaltrials-gov","external_id":"NCT04482465","title":"Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD","brief_summary":"Objectives: The investigators conducted a prospective study in Belgium with the objective to determine the proportion of subjects identified at moderate-to-high risk for AMD, based on the STARS® questionnaire, in need of nutritional supplementation by assessing their vitamin D, zinc oxide and fatty acid profile status. Methods: This multicentre epidemiological intervention pilot study involved 50 Belgian subjects with no AMD or early AMD, aged over 55, at moderate-to-high risk for AMD based on a simplified AMD risk assessment scale (STARS®) score ≥ 10, not taking vitamin D or trace nutrient containing supplements. Outcome data was collected during a one-time subject interview comprising of clinical eye examinations (typically visual acuity), the STARS® questionnaire, visual acuity assessment, an OCT scan on the macula, and fundus photography. Blood samples were collected from the patients and serum analysis was performed to determine the levels of omega-6 to omega-3 ratio, EPA and DHA, zinc and cupric oxide, and vitamin D, recognised as key nutrients involved in AMD pathophysiology.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universitaire Ziekenhuizen KU Leuven","enrollment":50,"countries":["Belgium"],"start_date":"2017-04-20","completion_date":"2017-10-05","last_update_date":"2024-06-27","source_url":"https://clinicaltrials.gov/study/NCT04482465","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"OVID-AMD","age_range":"55 Years to 95 Years","comparator":null,"organization":"Universitaire Ziekenhuizen KU Leuven","interventions":["blood sample"],"registry_source":"ClinicalTrials.gov","outcome_measures":["concentration of vitamin D — at the time of the procedure","concentration of fatty acids — at the time of the procedure","concentration of zinc oxide — at the time of the procedure"],"design_description":"NA · SINGLE GROUP · PREVENTION · NONE","source_has_results":false},"controlled_terms":["Age-related Macular Degeneration","Vitamin D Deficiency","blood sample"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct04482465","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2017-04-20 to 2017-10-05","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years to 95 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.901Z","intervention":["blood sample"],"participants":50,"study_design":"NA · SINGLE GROUP · PREVENTION · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["concentration of vitamin D — at the time of the procedure","concentration of fatty acids — at the time of the procedure","concentration of zinc oxide — at the time of the procedure"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41970","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}