{"type":"trials","record":{"id":41972,"source_id":"clinicaltrials-gov","external_id":"NCT06465212","title":"Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine by Matching Optometrist Office-based Sites With Clinical Supervision","brief_summary":"Office-based optometrist centres equipped with low-cost OCT devices can be used for screening of age-related macular degeneration. Matching next-door optometrist centres with clinical sites introduces a shared care service in an unprecedented and broad manner and offers timely and inclusive access to eye care for all citizens affected by the most frequent blinding disease in western countries. The aim of the study is to detect AMD in a next-door office-based setting on an individual level using low-cost OCT, through a telemedicine feedback loop. The specific aims of this study are: * Setting up a network of optometrist centres matched to clinical sites to perform shared care to protect eyesight in the elderly population. * Identify imaging biomarkers of age-related macular degeneration from OCT imaging. * Give a risk estimation of progression using a one-time low-cost OCT scan","overall_status":"Unknown","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Medical University of Vienna","enrollment":5000,"countries":[],"start_date":"2024-07-01","completion_date":"2026-07-01","last_update_date":"2024-06-21","source_url":"https://clinicaltrials.gov/study/NCT06465212","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"PYRENEES","age_range":"55 Years to 99 Years","comparator":null,"organization":"Medical University of Vienna","interventions":["TopCon Maestro 2 OCT"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Identification of different AMD stages on OCT images from a community-based setting to calculate the real-world prevale…","Further biomarkers of AMD that are expected to be present in the cohort will be analyzed in order to assess whether the…","As a post-hoc analysis, the diagnostic accuracy of AI algorithms to recognize changes associated with age-related macul…"],"design_description":null,"source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","TopCon Maestro 2 OCT"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct06465212","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-07-01 to 2026-07-01","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years to 99 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.901Z","intervention":["TopCon Maestro 2 OCT"],"participants":5000,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Identification of different AMD stages on OCT images from a community-based setting to calculate the real-world prevale…","Further biomarkers of AMD that are expected to be present in the cohort will be analyzed in order to assess whether the…","As a post-hoc analysis, the diagnostic accuracy of AI algorithms to recognize changes associated with age-related macul…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41972","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}