{"type":"trials","record":{"id":42140,"source_id":"clinicaltrials-gov","external_id":"NCT03024424","title":"Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMD","brief_summary":"The goals of this study are: To assess the impact of genetic testing based on how it alters behaviors, to assess the utility of serum biomarker measurement in combination with genetic testing, to assess the utility of genetic counseling in personal analysis of risk for age-related macular degeneration (AMD), and to assess the impact of presymptomatic genetic testing for choroidal neovascularization (CNV).","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Utah","enrollment":16,"countries":["United States"],"start_date":"2016-03-01","completion_date":"2017-08-10","last_update_date":"2023-05-06","source_url":"https://clinicaltrials.gov/study/NCT03024424","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years to 64 Years","comparator":"Late disclosure","organization":"University of Utah","interventions":["Early disclosure","Late disclosure"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in carotenoid levels in the skin — Twelve months","Change in carotenoid levels in the eyes — Twelve months"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · TRIPLE","source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration","Choroidal Neovascularization","Genetic Counseling","Early disclosure","Late disclosure"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct03024424","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-03-01 to 2017-08-10","comparator":"Late disclosure","confidence":"structured-source","population":"ALL · 18 Years to 64 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.926Z","intervention":["Early disclosure","Late disclosure"],"participants":16,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · TRIPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in carotenoid levels in the skin — Twelve months","Change in carotenoid levels in the eyes — Twelve months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42140","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}