{"type":"trials","record":{"id":42162,"source_id":"clinicaltrials-gov","external_id":"NCT04268836","title":"Vision Improvement for Patients With Age-Related Macular Degeneration","brief_summary":"The purpose of this study is to determine whether the Optimal Acuity Clear-K® Low Vision Aid System provides a safe and effective treatment to improve vision for patients with age-related macular degeneration.","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Optimal Acuity Corporation","enrollment":200,"countries":["Canada"],"start_date":"2024-01-09","completion_date":"2025-05-01","last_update_date":"2023-03-22","source_url":"https://clinicaltrials.gov/study/NCT04268836","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"AMD","age_range":"50 Years to 100 Years","comparator":null,"organization":"Optimal Acuity Corporation","interventions":["Optimal Acuity Clear-K® Low Vision Aid System treatment"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Best spectacle-corrected distance visual acuity (CDVA) changes from baseline to 24 months post-Tx — Through study compl…","Visual Function Questionnaire (VFQ)-25 quality of life assessment — Through study completion, an average of 2 years"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Age-related Macular Degeneration","Optimal Acuity Clear-K® Low Vision Aid System treatment"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct04268836","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-01-09 to 2025-05-01","comparator":null,"confidence":"structured-source","population":"ALL · 50 Years to 100 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.928Z","intervention":["Optimal Acuity Clear-K® Low Vision Aid System treatment"],"participants":200,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Best spectacle-corrected distance visual acuity (CDVA) changes from baseline to 24 months post-Tx — Through study compl…","Visual Function Questionnaire (VFQ)-25 quality of life assessment — Through study completion, an average of 2 years"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42162","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}