{"type":"trials","record":{"id":42165,"source_id":"clinicaltrials-gov","external_id":"NCT05433766","title":"Patient-centred Smartphone AI for Protecting Vision in Macular Disease","brief_summary":"Macular disease is the leading cause of blindness in the UK and age-related macular degeneration must undergo monitoring to determine if an injection into the eye is required that month \\[required in 50% of visits\\] - these patients are the 'frequent fliers' within ophthalmology units, visiting specialist hospital clinics on a monthly or bi-monthly basis. This project aims to create a home-monitoring algorithm that could in the future, enable the movement of 'monitoring' of chronic eye disease into the patients' homes: remotely identifying who does need an in-person appointment, and who can safely stay away from hospital.","overall_status":"Unknown","phases":[],"study_type":"OBSERVATIONAL","sponsor":"OKKO Health","enrollment":500,"countries":["United Kingdom"],"start_date":"2023-03-08","completion_date":"2024-04-01","last_update_date":"2023-03-10","source_url":"https://clinicaltrials.gov/study/NCT05433766","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":null,"comparator":null,"organization":"OKKO Health","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in visual status — 12 months continuous use","Impact of the OKKO Health app on Health literacy — 3-6 months of app use","Patient engagement with OKKO Health app — 12 months continuous use","To explore the correlation of varying demographic and lifestyle factors on AMD disease progression — 12 months continuo…"],"design_description":null,"source_has_results":false},"controlled_terms":["Age-Related Macular Degeneration"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05433766","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-03-08 to 2024-04-01","comparator":null,"confidence":"structured-source","population":"ALL","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.929Z","intervention":[],"participants":500,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in visual status — 12 months continuous use","Impact of the OKKO Health app on Health literacy — 3-6 months of app use","Patient engagement with OKKO Health app — 12 months continuous use","To explore the correlation of varying demographic and lifestyle factors on AMD disease progression — 12 months continuo…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42165","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}