{"type":"trials","record":{"id":42177,"source_id":"clinicaltrials-gov","external_id":"NCT05202587","title":"The Evaluation of the Agreement Between the NVHO in the Automatic Fluid Quantification and Cirrus OCT","brief_summary":"This multi-center study will enroll Adult subjects diagnosed with neo-vascular age-related macular degeneration (NV-AMD) in at least one eye at the time of enrollment. the subject study duration for this study is one day (2-3 hours). Each study site will have two NVHO devices and one Cirrus 5000 and the patients will be scand on the two NVHO devices and one Cirrus device as a part of the study flow. At the Study Visit, fluid must be present in approximately 280 study eyes and fluid must be absent from 20 study eyes. Each subject will only have one study eye. The fluid status will be determined by the investigator while reviewing an acceptable screening Cirrus OCT volume scan.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Notal Vision Inc.","enrollment":386,"countries":["United States"],"start_date":"2021-11-10","completion_date":"2023-01-12","last_update_date":"2023-02-15","source_url":"https://clinicaltrials.gov/study/NCT05202587","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"Notal Vision Inc.","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Intra-Retinal Fluid (IRF) — 5 minutes","Sub-Retinal Fluid (SRF) — 5 minutes","IRF spatial distribution — 5 minutes","SRF spatial distribution — 5 minutes","IRF area segmentation — 5 minutes","SRF area segmentation — 5 minutes","Mean central retinal thickness — 5 minutes"],"design_description":null,"source_has_results":false},"controlled_terms":["Neovascular Age-related Macular Degeneration"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Abstract contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05202587","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-11-10 to 2023-01-12","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.931Z","intervention":[],"participants":386,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Intra-Retinal Fluid (IRF) — 5 minutes","Sub-Retinal Fluid (SRF) — 5 minutes","IRF spatial distribution — 5 minutes","SRF spatial distribution — 5 minutes","IRF area segmentation — 5 minutes","SRF area segmentation — 5 minutes","Mean central retinal thickness — 5 minutes"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Abstract supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["abstract","controlled terminology","abstract context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42177","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}