{"type":"trials","record":{"id":42272,"source_id":"clinicaltrials-gov","external_id":"NCT02510885","title":"SD-OCT Angiography","brief_summary":"The objective of this study is to image retinal vascular alterations in patients with retinal disease using the AngioVue OCT-A system and understand the information these images provide. The investigators will image study participants who have retinal diseases with the AngioVue unit (Optovue) and will collect relevant clinical data to understand the nature of the information contained in images obtained on AngioVue. This study being conducted under an abbreviated IDE. The investigators will analyze data using descriptive statistics. Risks related to light exposure will be managed by ensuring that the exposure to the AngioVue light source is well below maximum permissible limits for safe exposure.","overall_status":"Terminated","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Duke University","enrollment":39,"countries":["United States"],"start_date":"2015-07-01","completion_date":"2019-03-11","last_update_date":"2022-04-19","source_url":"https://clinicaltrials.gov/study/NCT02510885","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"Duke University","interventions":["AngioVue SD-OCT"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Number of Participants With Image Quality Sensitive Enough to Identify Specific New Vessel Morphology — Day 0"],"design_description":"NA · SINGLE GROUP · OTHER · NONE","source_has_results":true},"controlled_terms":["Neovascular Age-related Macular Degeneration","Age-related Macular Degeneration","Diabetic Retinopathy","Retinal Vein Occlusion","Diabetic Macular Edema","AngioVue SD-OCT"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct02510885","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2015-07-01 to 2019-03-11","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.944Z","intervention":["AngioVue SD-OCT"],"participants":39,"study_design":"NA · SINGLE GROUP · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Number of Participants With Image Quality Sensitive Enough to Identify Specific New Vessel Morphology — Day 0"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42272","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}