{"type":"trials","record":{"id":42278,"source_id":"clinicaltrials-gov","external_id":"NCT05281042","title":"Home OCT Repeatability and Reproducibility of Automatic Fluid Quantification Study","brief_summary":"The study will enroll up to 30 AMD patients diagnosed with NV-AMD in at least one eye at the time of enrollment. At the Study Visit, fluid must be present in at least one eye of the subjects. If only one eye qualifies for enrollment, that will be assigned as the study eye. If both eyes are eligible, the study eye will be assigned according to a randomization schedule. Only one eye of each subject will be enrolled in the study. All subjects will be enrolled at 1 site in the United States. Subjects must meet all inclusion and no exclusion criteria.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Notal Vision Inc.","enrollment":20,"countries":["United States"],"start_date":"2021-09-13","completion_date":"2022-01-05","last_update_date":"2022-04-05","source_url":"https://clinicaltrials.gov/study/NCT05281042","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"Notal Vision Inc.","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Notal Home OCT Total Retinal Fluid (TRF) amount measured by NOA — 5 minutes","Notal Home OCT Intra-Retinal Fluid (IRF) amount measured by NOA — 5 minutes","Notal Home OCT Sub-Retinal Fluid (SRF) amount measured by NOA — 5 minutes","Zeiss Cirrus OCT Total Retinal Fluid (TRF) amount measured by a human reader — 5 minutes","Zeiss Cirrus OCT Intra-Retinal Fluid (IRF) amount measured by a human reader — 5 minutes","Zeiss Cirrus OCT Sub-Retinal Fluid (SRF) amount measured by a human reader — 5 minutes","Subjects who completed self-scanning on the Notal Home OCT, following a self-tutorial. — 5 minuts"],"design_description":null,"source_has_results":false},"controlled_terms":["Neovascular Age-related Macular Degeneration"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct05281042","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-09-13 to 2022-01-05","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.945Z","intervention":[],"participants":20,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Notal Home OCT Total Retinal Fluid (TRF) amount measured by NOA — 5 minutes","Notal Home OCT Intra-Retinal Fluid (IRF) amount measured by NOA — 5 minutes","Notal Home OCT Sub-Retinal Fluid (SRF) amount measured by NOA — 5 minutes","Zeiss Cirrus OCT Total Retinal Fluid (TRF) amount measured by a human reader — 5 minutes","Zeiss Cirrus OCT Intra-Retinal Fluid (IRF) amount measured by a human reader — 5 minutes","Zeiss Cirrus OCT Sub-Retinal Fluid (SRF) amount measured by a human reader — 5 minutes","Subjects who completed self-scanning on the Notal Home OCT, following a self-tutorial. — 5 minuts"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42278","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}