{"type":"trials","record":{"id":42691,"source_id":"clinicaltrials-gov","external_id":"NCT05865340","title":"To Exam the Efficacy of Oral Health and Mediterranean Diet Interventions in Preventing Cognitive Decline Among Older Adults With Mild Cognitive Impairment","brief_summary":"At present, many literatures have confirmed that the Mediterranean diet has the effect of delaying cognitive degeneration in patients with mild cognitive impairment, and can also slow down the speed of brain atrophy. In addition to the highly respected Mediterranean diet every year, several years of foreign research have found The maintenance of oral hygiene also has a significant relationship with the decline of cognitive function. The intervention of \"oral hygiene\" is a new intervention method that has started in recent years. Oral health will affect the overall health status, physical function, diet and nutritional status of the elderly. In particular, older adults with poor oral health are more likely to suffer from mild cognitive impairment. The relationship between oral health and nutrition and overall health is inseparable. If the concept of healthy eating (Mediterranean diet) recognized by the public is used and oral health education is involved at the same time. To allow patients with mild cognitive impairment to maintain oral health care in daily life, and to increase the knowledge of the Mediterranean diet and try to follow the rules of the Mediterranean diet, whether there is a more significant impact on these patients.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Taipei Veterans General Hospital, Taiwan","enrollment":45,"countries":["Taiwan"],"start_date":"2023-05-15","completion_date":"2023-12-31","last_update_date":"2024-08-09","source_url":"https://clinicaltrials.gov/study/NCT05865340","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:36.493571+00:00","last_seen_at":"2026-09-25T06:25:45.678+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"50 Years","comparator":"compare","organization":"Taipei Veterans General Hospital, Taiwan","interventions":["oral health + MED diet","oral health","MED diet"],"registry_source":"ClinicalTrials.gov","outcome_measures":["cognitive — 6 months","diet — 6 months","oral health — 6 months","frailty — 6 months"],"design_description":"RANDOMIZED · PARALLEL · OTHER · NONE","source_has_results":false},"controlled_terms":["Mild Cognitive Impairment (MCI)","Oral Health","Mediterranean Diet","oral health + MED diet","oral health","MED diet"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: oral health.","quality_checked_at":"2026-09-25T06:25:48.368501+00:00","duplicate_cluster_key":"id:nct05865340","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-05-15 to 2023-12-31","comparator":"compare","confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:45.719Z","intervention":["oral health + MED diet","oral health","MED diet"],"participants":45,"study_design":"RANDOMIZED · PARALLEL · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["cognitive — 6 months","diet — 6 months","oral health — 6 months","frailty — 6 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"mediterranean-diet","is_published":true,"match_reasons":["Title contains controlled term: mediterranean diet.","Abstract contains controlled term: mediterranean diet.","Source terminology contains: mediterranean diet.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Mediterranean diet","slug":"mediterranean-diet"}},{"topic_slug":"oral-health-aging","is_published":true,"match_reasons":["Title contains controlled term: oral health.","Abstract contains controlled term: oral health.","Source terminology contains: oral health.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Oral health and ageing","slug":"oral-health-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/42691","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}