{"type":"trials","record":{"id":440,"source_id":"clinicaltrials-gov","external_id":"NCT07466953","title":"Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality","brief_summary":"This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis. Forty adult participants will receive intradermal exosome applications in three treatment sessions performed at one-month intervals. Facial skin analysis will be conducted using the VISIA imaging system before each treatment session and six months after the final treatment. The study will examine changes in multiple facial skin characteristics including wrinkles, pigmentation, skin texture, pores, UV spots, red areas, brown spots, and porphyrins to determine whether exosome therapy may improve overall facial skin quality.","overall_status":"Not Yet Recruiting","phases":["PHASE3"],"study_type":"INTERVENTIONAL","sponsor":"Mert Ersan","enrollment":40,"countries":[],"start_date":"2026-07-10","completion_date":"2026-12-31","last_update_date":"2026-08-07","source_url":"https://clinicaltrials.gov/study/NCT07466953","editorial_summary":"A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:45:04.929625+00:00","last_seen_at":"2026-09-15T00:18:36.032+00:00","metadata":{"acronym":null,"organization":"Yeditepe University Hospital","source_has_results":false},"controlled_terms":[],"relevance_confidence":68,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Published automatically with 68% topic confidence after controlled-term evaluation.","quality_checked_at":"2026-09-15T02:15:56.576005+00:00","duplicate_cluster_key":"registry:nct07466953","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"stem-cells","is_published":true,"match_reasons":["Legacy trial evaluated automatically against controlled title, summary, and longevity-context rules."],"matched_fields":["abstract"],"relevance_score":68,"intelligence_topics":{"name":"Stem cells","slug":"stem-cells"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/440","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}