{"type":"trials","record":{"id":44024,"source_id":"clinicaltrials-gov","external_id":"NCT05756478","title":"Appropriate Prescribing for Older Adults With Multimorbidity (Pro-M)","brief_summary":"This is a two-site feasibility study to test implementation of an intervention that aims to reduce inappropriate prescribing for older adults with multimorbidity in geriatric medicine specialist clinics at public hospitals in Singapore. The specific aims are: 1. To assess the implementation outcomes: Appropriateness, Penetration/Reach, Acceptability, Feasibility, Sustainability (primary) 2. To collect data on recruitment and pre-post data on prevalence of potentially inappropriate prescribing (PIP) for the purpose of determining sample size for a scale up next phase study (secondary). 3. To conduct cost analysis of the intervention (secondary).","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Geriatric Education and Research Institute","enrollment":36,"countries":["Singapore"],"start_date":"2023-02-01","completion_date":"2023-10-16","last_update_date":"2024-02-09","source_url":"https://clinicaltrials.gov/study/NCT05756478","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:45.944732+00:00","last_seen_at":"2026-09-25T06:25:30.723+00:00","metadata":{"sex":"ALL","acronym":"Pro-M","age_range":"21 Years to 99 Years","comparator":null,"organization":"Geriatric Education and Research Institute","interventions":["Medication review"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Patients' attitudes towards acceptance of the intervention (Penetration/Reach) — A single-time-point survey to be admin…","Implementers' attitudes towards the appropriateness of the intervention — 3-month Evaluation period: A single-time-poin…","Implementers' attitudes towards the acceptability of the intervention — 3-month Evaluation period: A single-time-point…","Implementers' attitudes towards the feasibility of the intervention. — 3-month Evaluation period: A single-time-point s…","Implementers' attitudes towards the sustainability of the intervention. — 3-month Evaluation period: A single-time-poin…","Implementers' views on the fidelity of the intervention. — :3-month Evaluation period: A single-time-point survey to be…","Recruitment rate — 6 months during implementation period","Effectiveness of the intervention: Percentage of patients with at least one PIM before and after intervention. — 6 mont…","Effectiveness of the intervention: Percentage of patients with other medication issues identified before and after inte…","Manpower cost to conduct medication review — 6 months during implementation period","Cost of PIM and other medications with issues identified before and after medication review. — 6 months during implemen…"],"design_description":"NA · SINGLE GROUP · HEALTH SERVICES RESEARCH · NONE","source_has_results":false},"controlled_terms":["Potentially Inappropriate Medications","Multimorbidity","Polypharmacy","Medication review"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: multimorbidity.","quality_checked_at":"2026-09-25T06:25:35.871646+00:00","duplicate_cluster_key":"id:nct05756478","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-02-01 to 2023-10-16","comparator":null,"confidence":"structured-source","population":"ALL · 21 Years to 99 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:30.749Z","intervention":["Medication review"],"participants":36,"study_design":"NA · SINGLE GROUP · HEALTH SERVICES RESEARCH · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Patients' attitudes towards acceptance of the intervention (Penetration/Reach) — A single-time-point survey to be admin…","Implementers' attitudes towards the appropriateness of the intervention — 3-month Evaluation period: A single-time-poin…","Implementers' attitudes towards the acceptability of the intervention — 3-month Evaluation period: A single-time-point…","Implementers' attitudes towards the feasibility of the intervention. — 3-month Evaluation period: A single-time-point s…","Implementers' attitudes towards the sustainability of the intervention. — 3-month Evaluation period: A single-time-poin…","Implementers' views on the fidelity of the intervention. — :3-month Evaluation period: A single-time-point survey to be…","Recruitment rate — 6 months during implementation period","Effectiveness of the intervention: Percentage of patients with at least one PIM before and after intervention. — 6 mont…","Effectiveness of the intervention: Percentage of patients with other medication issues identified before and after inte…","Manpower cost to conduct medication review — 6 months during implementation period","Cost of PIM and other medications with issues identified before and after medication review. — 6 months during implemen…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"multimorbidity","is_published":true,"match_reasons":["Title contains controlled term: multimorbidity.","Abstract contains controlled term: multimorbidity.","Source terminology contains: multimorbidity.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Multimorbidity","slug":"multimorbidity"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/44024","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}