{"type":"trials","record":{"id":44062,"source_id":"clinicaltrials-gov","external_id":"NCT04842396","title":"Low-volume Cycling Training in Older People With Multimorbidity","brief_summary":"INTRODUCTION: Physical exercise, when practiced regularly and in adequate doses, is a proven nonpharmacological measure that helps to prevent and reverse noncommunicable diseases, as well as reduce mortality rates from any cause. In general, older adults perform insufficient physical activity and do not meet the doses recommended by the World Health Organization for the improvement of health through physical activity. OBJECTIVE: Our main aim will be to evaluate the effect of a 6-week intervention on health-related outcomes (body composition, hemodynamic and functionality changes) in 24 individuals aged 65 and older with multimorbidity. METHODS AND ANALYSIS: The study was a 2 x 2 randomized controlled trial using a two-group design (exercise vs. control) and two repeated measures (pre- vs. postintervention). The intervention (on the MOTOmed Muvi) will consist of a very low volume (60 minutes per week) of low-to-moderate intensity exercise training to assess body composition evaluation, hemodynamic parameter evaluation and functional evaluation. Participants will be recruited at the Gerontological Complex La Milagrosa (A Coruña, Spain), consisting of a daycare center and a nursing home. For the statistical analysis, nonparametric ANOVA type statistics and mixed models for repeated measures will be used.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universidade da Coruña","enrollment":24,"countries":["Spain"],"start_date":"2019-09-01","completion_date":"2019-12-10","last_update_date":"2021-10-04","source_url":"https://clinicaltrials.gov/study/NCT04842396","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:45.944732+00:00","last_seen_at":"2026-09-25T06:25:30.723+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"Control group","organization":"Universidade da Coruña","interventions":["Experimental:Motorized cycle ergometer"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Body weight — 6 weeks","Muscle mass — 6 weeks","Fat mass — 6 week","Fat mass percentage — 6 week","Waist circumference — 6 weeks","Heart rate — 6 weeks","Systolic blood pressure — 6 weeks","Diastolic blood pressure — 6 weeks","Mean blood pressure — 6 weeks","The Performance-Oriented Mobility Assessment (POMA) — 6 weeks","The Short Physical Performance Battery test (SPPB) — 6 weeks","Chair Sit-and-Reach Test (CSR) — 6 weeks","Frailty — 6 weeks"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Frailty","Morbidity, Multiple","Experimental:Motorized cycle ergometer"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: multimorbidity.","quality_checked_at":"2026-09-25T06:25:35.871646+00:00","duplicate_cluster_key":"id:nct04842396","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-09-01 to 2019-12-10","comparator":"Control group","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:30.757Z","intervention":["Experimental:Motorized cycle ergometer"],"participants":24,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Body weight — 6 weeks","Muscle mass — 6 weeks","Fat mass — 6 week","Fat mass percentage — 6 week","Waist circumference — 6 weeks","Heart rate — 6 weeks","Systolic blood pressure — 6 weeks","Diastolic blood pressure — 6 weeks","Mean blood pressure — 6 weeks","The Performance-Oriented Mobility Assessment (POMA) — 6 weeks","The Short Physical Performance Battery test (SPPB) — 6 weeks","Chair Sit-and-Reach Test (CSR) — 6 weeks","Frailty — 6 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"multimorbidity","is_published":true,"match_reasons":["Title contains controlled term: multimorbidity.","Abstract contains controlled term: multimorbidity.","Title supplies longevity context: older people.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Multimorbidity","slug":"multimorbidity"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/44062","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}