{"type":"trials","record":{"id":44284,"source_id":"clinicaltrials-gov","external_id":"NCT03263234","title":"Circadian Adjusted LED Light's Effect in People Living in Elderly Housing","brief_summary":"Europe is undergoing a demographic change with a rapidly growing population of 65 years+. This challenges municipalities and hospitals as the ageing citizens need care and treatment due to an age-related decline in physical and mental capacity. Therefore municipalities are experiencing a growing need for sufficient and customized housing, which can support the elderly citizens in sustaining well-being and health along with preventing functional decline. Well-fare technologies, such as Circadian adjusted LED-based lighting (CALED), are suggested as a remedy for this. To obtain proper visual sharpness and better contrast, people of older age require heightened light levels due to age-related failing vision. Furthermore, inappropriate light at night disrupts not only sleep but also the timing of the circadian rhythm, with negative consequences on cognition and emotions. Therefore CALED is being increasingly considered for use in hospitals and elderly housing because of its wide spectrum of wavelengths, good contrast and fast switching, and possibility to support a normalised circadian rhythm. Lighting based on LED has been shown to improve the quality of sleep and to improve well-being in the elderly. However, it is not known whether CALED mimicking a normal circadian rhythm has the same benefits for elderly persons with frailty or dementia. The investigators therefore want to test the effects of CALED in elderly people with frailty and mobility disabilities and/or dementia living in elderly housing. The investigators hypothesise that CALED can improve sleep and well-being in both elderly with frailty and dementia.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Ove Andersen","enrollment":34,"countries":["Denmark"],"start_date":"2017-09-29","completion_date":"2018-04-22","last_update_date":"2020-03-12","source_url":"https://clinicaltrials.gov/study/NCT03263234","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:48.846222+00:00","last_seen_at":"2026-09-25T06:25:39.067+00:00","metadata":{"sex":"ALL","acronym":"Lightel","age_range":"50 Years","comparator":"Group 1; Group 2; Group 3. Control group","organization":"Hvidovre University Hospital","interventions":["8 weeks of circadian adjusted LED-based lighting (CALED)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["The average difference in Pittsburgh Sleep Quality Index (PSQI) between the end of the intervention period and the end…","The average difference in plasma soluble urokinase plasminogen receptor (suPAR) between the end of the intervention per…","The average difference in 24-hour mobility between the end of the intervention period and the end of the control period…","The average difference in Epwoth Sleepiness Scale between the end of the intervention period and the end of the control…","The average difference in inflammatory biomarkers such as interleukin (IL)-6, IL-10, soluble CD14, and C reactive prote…","The average difference in endocrinologic biomarkers such as insulin, glucose, cortisol, leptin and melatonin between th…","The average difference in the Mini Mental State Examination between the end of the intervention period and the end of t…","The average difference in the Major Depression Inventory (MDI) between the end of the intervention period and the end o…","The average difference in the Health related quality of life by the EuroQol (EQ-5D-3L) between the end of the intervent…","The average difference in Activities of Daily living by the Barthel 20 index between the end of the intervention period…"],"design_description":"RANDOMIZED · CROSSOVER · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Elderly Housing Residents With Frailty or Dementia","8 weeks of circadian adjusted LED-based lighting (CALED)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: circadian.","quality_checked_at":"2026-09-25T06:25:42.287439+00:00","duplicate_cluster_key":"id:nct03263234","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2017-09-29 to 2018-04-22","comparator":"Group 1; Group 2; Group 3. Control group","confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:39.113Z","intervention":["8 weeks of circadian adjusted LED-based lighting (CALED)"],"participants":34,"study_design":"RANDOMIZED · CROSSOVER · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["The average difference in Pittsburgh Sleep Quality Index (PSQI) between the end of the intervention period and the end…","The average difference in plasma soluble urokinase plasminogen receptor (suPAR) between the end of the intervention per…","The average difference in 24-hour mobility between the end of the intervention period and the end of the control period…","The average difference in Epwoth Sleepiness Scale between the end of the intervention period and the end of the control…","The average difference in inflammatory biomarkers such as interleukin (IL)-6, IL-10, soluble CD14, and C reactive prote…","The average difference in endocrinologic biomarkers such as insulin, glucose, cortisol, leptin and melatonin between th…","The average difference in the Mini Mental State Examination between the end of the intervention period and the end of t…","The average difference in the Major Depression Inventory (MDI) between the end of the intervention period and the end o…","The average difference in the Health related quality of life by the EuroQol (EQ-5D-3L) between the end of the intervent…","The average difference in Activities of Daily living by the Barthel 20 index between the end of the intervention period…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: circadian.","Abstract contains controlled term: sleep, circadian.","Source terminology contains: circadian.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/44284","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}