{"type":"trials","record":{"id":44316,"source_id":"clinicaltrials-gov","external_id":"NCT00427323","title":"Light Exposure to Treat Sleep Disruption in Older People","brief_summary":"The purpose of this study is to test whether shifts in the timing of the biological clock to a later hour (phase delay shifts of the human circadian system) can be produced in response to four successive evenings of light exposure, and whether that phase shift will result in greater evening alertness and greater nighttime sleep efficiency. Three different light sources will be compared: 1) standard fluorescent light; 2) blue-enriched light; 3) incandescent fluorescent light.","overall_status":"Suspended","phases":[],"study_type":"INTERVENTIONAL","sponsor":"National Institute on Aging (NIA)","enrollment":60,"countries":["United States"],"start_date":"2006-06-01","completion_date":"2007-09-01","last_update_date":"2009-12-11","source_url":"https://clinicaltrials.gov/study/NCT00427323","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Suspended. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:48.846222+00:00","last_seen_at":"2026-09-25T06:25:39.067+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"55 Years to 80 Years","comparator":null,"organization":"National Institute on Aging (NIA)","interventions":["light exposure"],"registry_source":"ClinicalTrials.gov","outcome_measures":["change in sleep efficiency","shift of circadian phase of melatonin secretion","change in alertness and performance"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Sleep Initiation and Maintenance Disorders","Circadian Rhythm Sleep Disorders","Hypersomnia","light exposure"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: sleep.","quality_checked_at":"2026-09-25T06:25:42.287439+00:00","duplicate_cluster_key":"id:nct00427323","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2006-06-01 to 2007-09-01","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:39.118Z","intervention":["light exposure"],"participants":60,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["change in sleep efficiency","shift of circadian phase of melatonin secretion","change in alertness and performance"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: sleep.","Abstract contains controlled term: sleep, circadian.","Source terminology contains: sleep, circadian.","Title supplies longevity context: older people.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/44316","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}