{"type":"trials","record":{"id":446,"source_id":"clinicaltrials-gov","external_id":"NCT07708870","title":"Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer","brief_summary":"This two-phase study aims to examine the current status of older adults with newly diagnosed locally advanced or advanced non-small cell lung cancer and their primary family caregivers, and to evaluate the effects of the Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model (ICSM). Phase I is a cross-sectional correlational study assessing distress, unmet care needs, resource awareness and utilization, social support, and health promotion practice. Phase II is a two-group randomized controlled trial comparing ICSM plus oncology case manager care with oncology case manager care and usual hospital care. The intervention includes nurse-led education and counseling, symptom management, emotional coping, problem-solving, social resource use, caregiving activity arrangement, and use of a web-based or LINE-based integrated resource system.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"National Taiwan University Hospital","enrollment":120,"countries":["Taiwan"],"start_date":"2025-04-08","completion_date":"2027-06-01","last_update_date":"2026-07-16","source_url":"https://clinicaltrials.gov/study/NCT07708870","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:45:04.929625+00:00","last_seen_at":"2026-09-25T06:05:08.502+00:00","metadata":{"sex":"ALL","acronym":"ICSM","age_range":"18 Years","comparator":"Oncology Case Manager Care and Usual Care","organization":"National Taiwan University Hospital","interventions":["Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model","Oncology Case Manager Care and Usual Care"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Caregiver Quality of Life as Measured by the Caregiver Quality of Life Index-Cancer (CQOLC) — Baseline, 2 wee…","Change in Caregiver Resource Utilization as Measured by the Resource and Utilization Assessment Scale — Baseline, 2 wee…","Change in Caregiver Strain as Measured by the Caregiver Strain Index — Baseline, 2 weeks, 1 month, 3 months, 6 months,…","Change in Caregiver Anxiety as Measured by the Generalized Anxiety Disorder-7 Scale — Baseline, 2 weeks, 1 month, 3 mon…","Change in Caregiver Depressive Symptoms as Measured by the Patient Health Questionnaire-9 — Baseline, 2 weeks, 1 month,…","Change in Caregiver Sleep Quality as Measured by the Pittsburgh Sleep Quality Index — Baseline, 2 weeks, 1 month, 3 mon…","Change in Patient Quality of Life and Lung Cancer-Related Symptoms as Measured by the EORTC QLQ-C30 and EORTC QLQ-LC13…","Change in Patient Supportive Care Needs as Measured by the Supportive Care Needs Survey-Screening Tool Chinese Version…"],"design_description":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Non-Small Cell Lung Cancer","Advanced Lung Cancer","Caregiver Burden","Resource Utilization","Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model","Oncology Case Manager Care and Usual Care"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: cancer.","quality_checked_at":"2026-09-25T06:05:13.559725+00:00","duplicate_cluster_key":"id:nct07708870","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-04-08 to 2027-06-01","comparator":"Oncology Case Manager Care and Usual Care","confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:08.508Z","intervention":["Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model","Oncology Case Manager Care and Usual Care"],"participants":120,"study_design":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Caregiver Quality of Life as Measured by the Caregiver Quality of Life Index-Cancer (CQOLC) — Baseline, 2 wee…","Change in Caregiver Resource Utilization as Measured by the Resource and Utilization Assessment Scale — Baseline, 2 wee…","Change in Caregiver Strain as Measured by the Caregiver Strain Index — Baseline, 2 weeks, 1 month, 3 months, 6 months,…","Change in Caregiver Anxiety as Measured by the Generalized Anxiety Disorder-7 Scale — Baseline, 2 weeks, 1 month, 3 mon…","Change in Caregiver Depressive Symptoms as Measured by the Patient Health Questionnaire-9 — Baseline, 2 weeks, 1 month,…","Change in Caregiver Sleep Quality as Measured by the Pittsburgh Sleep Quality Index — Baseline, 2 weeks, 1 month, 3 mon…","Change in Patient Quality of Life and Lung Cancer-Related Symptoms as Measured by the EORTC QLQ-C30 and EORTC QLQ-LC13…","Change in Patient Supportive Care Needs as Measured by the Supportive Care Needs Survey-Screening Tool Chinese Version…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"cancer-and-aging","is_published":true,"match_reasons":["Title contains controlled term: cancer.","Abstract contains controlled term: cancer.","Source terminology contains: cancer.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Cancer and ageing","slug":"cancer-and-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/446","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}