{"type":"trials","record":{"id":45440,"source_id":"clinicaltrials-gov","external_id":"NCT03696576","title":"Expiratory Muscle Strength Training and Phonation Resistance Training Exercises For Elderly Patients With Vocal Fold Atrophy","brief_summary":"The larynx and vocal folds undergo many age-related changes in their physiology and structure that can lead to undesirable effects on the voice, with changes in the respiratory system compounding these deficits. These changes, also called presbyphonia, can have serious detrimental effects on the lives of elderly individuals. There are few studies that have evaluated the use of voice therapy treatment options for these patients. The primary aim of this study is to test whether the addition of expiratory muscle strength training (EMST) to a current, validated voice therapy protocol aimed at treating presbyphonia, (phonation resistance training, PhoRTE) can improve outcomes of therapy.","overall_status":"Terminated","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Emory University","enrollment":24,"countries":["United States"],"start_date":"2018-09-20","completion_date":"2020-05-04","last_update_date":"2021-08-30","source_url":"https://clinicaltrials.gov/study/NCT03696576","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:30:14.100152+00:00","last_seen_at":"2026-09-25T03:15:26.54+00:00","metadata":{"acronym":null,"organization":"Emory University","source_has_results":true},"controlled_terms":["Voice Disorder","Vocal Cord Atrophy","Presbyphonia","EMST","PhoRTE"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: resistance training, strength training.","quality_checked_at":"2026-09-25T03:15:35.13451+00:00","duplicate_cluster_key":"id:nct03696576","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2018-09-20 to 2020-05-04","comparator":null,"confidence":"structured-source","population":null,"provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:38:00.457301+00:00","intervention":[],"participants":24,"study_design":"INTERVENTIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":[],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: resistance training, strength training.","Abstract contains controlled term: resistance training, strength training.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/45440","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}