{"type":"trials","record":{"id":45486,"source_id":"clinicaltrials-gov","external_id":"NCT04262674","title":"Non-invasive, Wearable Multi-parameter System for the Early Prediction of Cognitive Decline and Dementia in Older Adults","brief_summary":"This project develops an innovative screening system and prediction model to detect preclinical symptoms of cognitive impairment and predict the potential development of mild cognitive impairments and dementia in older adults. The earliest possible detection of preclinical symptoms is prerequisite to improve the efficacy of subsequent preventative non-pharmacological, life-style and exercise related, personalized treatment interventions.","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Empa, Swiss Federal Laboratories for Materials Science and Technology","enrollment":82,"countries":["Switzerland"],"start_date":"2019-09-23","completion_date":"2021-07-01","last_update_date":"2021-02-04","source_url":"https://clinicaltrials.gov/study/NCT04262674","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:30:14.100152+00:00","last_seen_at":"2026-09-25T03:15:46.32+00:00","metadata":{"acronym":null,"organization":"Empa, Swiss Federal Laboratories for Materials Science and Technology","source_has_results":false},"controlled_terms":["Mild Cognitive Impairment","Healthy Aging","Cognitive-motor training"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: wearable.","quality_checked_at":"2026-09-25T03:15:49.327669+00:00","duplicate_cluster_key":"id:nct04262674","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-09-23 to 2021-07-01","comparator":null,"confidence":"structured-source","population":null,"provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:38:00.457301+00:00","intervention":[],"participants":82,"study_design":"INTERVENTIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":[],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"digital-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: wearable.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Digital biomarkers","slug":"digital-biomarkers"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/45486","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}