{"type":"trials","record":{"id":46144,"source_id":"clinicaltrials-gov","external_id":"NCT04241900","title":"Effect of Aging and Aerobic Fitness Level on Heat Dissipation","brief_summary":"In the context of global aging, the health risk factors associated with exercising or working in the heat for aging population are exacerbated by the rising in global surface temperatures. The purpose of this investigation is to determine at what age the heat loss decrements occur and to examine if aerobic fitness level can affect the heat loss capacity in neutral environmental conditions.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Petros Dinas","enrollment":431,"countries":["Greece"],"start_date":"2014-05-01","completion_date":"2018-10-30","last_update_date":"2020-01-27","source_url":"https://clinicaltrials.gov/study/NCT04241900","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:30:18.816162+00:00","last_seen_at":"2026-09-25T07:05:20.248+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"9 Years to 60 Years","comparator":null,"organization":"University of Thessaly","interventions":["Shuttle run test"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Aerobic fitness level — Through study completion (a shuttle run test), an average of 15 minutes","Change from baseline ear canal temperature — Change from baseline to the end of study completion (a shuttle run test),…","Change from baseline axillary temperature — Change from baseline to the end of study completion (a shuttle run test), a…","Physical activity levels — Once before the shuttle run test","Change from baseline body weight — Change from baseline to the end of study completion (a shuttle run test), an average…","Change from baseline whole Body Sweat Rate — Change from baseline to the end of study completion (a shuttle run test),…","Air temperature — Up to 30 minutes, during a one complete shuttle run test","Relative humidity — Up to 30 minutes, during a one complete shuttle run test"],"design_description":"NA · SINGLE GROUP · PREVENTION · NONE","source_has_results":false},"controlled_terms":["Risk of Heat Stress","Shuttle run test"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: aerobic fitness.","quality_checked_at":"2026-09-25T07:05:30.295959+00:00","duplicate_cluster_key":"id:nct04241900","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2014-05-01 to 2018-10-30","comparator":null,"confidence":"structured-source","population":"ALL · 9 Years to 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T07:05:20.347Z","intervention":["Shuttle run test"],"participants":431,"study_design":"NA · SINGLE GROUP · PREVENTION · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Aerobic fitness level — Through study completion (a shuttle run test), an average of 15 minutes","Change from baseline ear canal temperature — Change from baseline to the end of study completion (a shuttle run test),…","Change from baseline axillary temperature — Change from baseline to the end of study completion (a shuttle run test), a…","Physical activity levels — Once before the shuttle run test","Change from baseline body weight — Change from baseline to the end of study completion (a shuttle run test), an average…","Change from baseline whole Body Sweat Rate — Change from baseline to the end of study completion (a shuttle run test),…","Air temperature — Up to 30 minutes, during a one complete shuttle run test","Relative humidity — Up to 30 minutes, during a one complete shuttle run test"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"aerobic-fitness","is_published":true,"match_reasons":["Title contains controlled term: aerobic fitness.","Abstract contains controlled term: aerobic fitness.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Aerobic fitness and VO2 max","slug":"aerobic-fitness"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/46144","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}