{"type":"trials","record":{"id":50714,"source_id":"clinicaltrials-gov","external_id":"NCT00690183","title":"Relationship Between Physical Activity and Stem Cells in Older Adults","brief_summary":"This is a pilot study to develop a collaborative, translational research project investigating whether physical activity may in part exert a positive influence on aging via the mobilization of stem cells. Preliminary data will be collected to explore the relationship between physical activity and stem cell populations found in the blood. The study hypothesis is that stem cell decrease with age, but that persons who are more physically active will have a higher number of stem cells in the blood. The first assessment will include an evaluation of health, physical activity and lifestyle via questionnaires. Height, weight and abdominal girth will be measured, and blood will be drawn for immune and stem cell assessment. Participants will be given a pedometer and accelerometer to wear daily for 7 days. Participants will return for a second visit at which the pedometer and accelerometer will be returned and blood will be drawn. Stem cell and immune assays will be repeated to evaluate the variability of these measures over time. The correlation between stem cell numbers and physical activity will be analyzed.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"University of Nebraska","enrollment":39,"countries":["United States"],"start_date":"2008-06-05","completion_date":"2008-10-01","last_update_date":"2023-09-28","source_url":"https://clinicaltrials.gov/study/NCT00690183","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:40:48.95077+00:00","last_seen_at":"2026-09-25T06:05:08.502+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years to 105 Years","comparator":null,"organization":"University of Nebraska","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["circulating stem cells — upon enrollment, one week later","physical activity — upon enrollment","alcohol consumption — upon enrollment","smoking history — upon enrollment","plasma cytokine levels — upon enrollment, one later"],"design_description":null,"source_has_results":false},"controlled_terms":["Aging"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: stem cell.","quality_checked_at":"2026-09-25T06:05:13.559725+00:00","duplicate_cluster_key":"id:nct00690183","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2008-06-05 to 2008-10-01","comparator":null,"confidence":"structured-source","population":"ALL · 60 Years to 105 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:08.531Z","intervention":[],"participants":39,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["circulating stem cells — upon enrollment, one week later","physical activity — upon enrollment","alcohol consumption — upon enrollment","smoking history — upon enrollment","plasma cytokine levels — upon enrollment, one later"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"stem-cells","is_published":true,"match_reasons":["Title contains controlled term: stem cell.","Abstract contains controlled term: stem cell.","Title supplies longevity context: older adult.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Stem cells","slug":"stem-cells"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/50714","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}