{"type":"trials","record":{"id":50801,"source_id":"clinicaltrials-gov","external_id":"NCT03928444","title":"Evaluation of the Efficacy and Tolerability of Autologous Adipose Tissue Derived Stem Cells on Facial Rejuvenation","brief_summary":"This study is to evaluate the efficacy and tolerability of autologous adipose tissue derived stem cells in facial rejuvenation.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Alexandria University","enrollment":15,"countries":["Egypt"],"start_date":"2019-01-01","completion_date":"2019-08-06","last_update_date":"2019-09-30","source_url":"https://clinicaltrials.gov/study/NCT03928444","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:40:48.95077+00:00","last_seen_at":"2026-09-25T06:05:08.502+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"35 Years","comparator":"control","organization":"Alexandria University","interventions":["intradermal injection of adipose derived stem cells to one side of the face","intradermal injection of saline to one side of the face"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Assessment of the degree of aesthetic improvement using the global aesthetic improvement scale GAIS 5-point scale where…","Assessment of trans-epidermal water loss (TEWL) in gm /h-m2 using noninvasive probe (Dermal measurement system EDS12, U…","Assessment of skin hydration in units using noninvasive probe (Dermal measurement system EDS12, UK) on both temple regi…","Measurement of epidermal thickness in mm using UBM (Ultrasound Bio microscopy) on both temple regions of the head — 6 m…","Measurement of dermal thickness in mm using UBM (Ultrasound Bio microscopy) on both temple regions of the head — 6 mont…","A visual analog scale, will be used to assess participants' satisfaction by the treatment and side effects — 6 months"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Skin Rejuvenation","intradermal injection of adipose derived stem cells to one side of the face","intradermal injection of saline to one side of the face"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: stem cell.","quality_checked_at":"2026-09-25T06:05:13.559725+00:00","duplicate_cluster_key":"id:nct03928444","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-01-01 to 2019-08-06","comparator":"control","confidence":"structured-source","population":"FEMALE · 35 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:08.543Z","intervention":["intradermal injection of adipose derived stem cells to one side of the face","intradermal injection of saline to one side of the face"],"participants":15,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Assessment of the degree of aesthetic improvement using the global aesthetic improvement scale GAIS 5-point scale where…","Assessment of trans-epidermal water loss (TEWL) in gm /h-m2 using noninvasive probe (Dermal measurement system EDS12, U…","Assessment of skin hydration in units using noninvasive probe (Dermal measurement system EDS12, UK) on both temple regi…","Measurement of epidermal thickness in mm using UBM (Ultrasound Bio microscopy) on both temple regions of the head — 6 m…","Measurement of dermal thickness in mm using UBM (Ultrasound Bio microscopy) on both temple regions of the head — 6 mont…","A visual analog scale, will be used to assess participants' satisfaction by the treatment and side effects — 6 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"stem-cells","is_published":true,"match_reasons":["Title contains controlled term: stem cell.","Abstract contains controlled term: stem cell.","Source terminology contains: stem cell.","Title supplies longevity context: rejuvenation.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Stem cells","slug":"stem-cells"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/50801","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}