{"type":"trials","record":{"id":50846,"source_id":"clinicaltrials-gov","external_id":"NCT02107118","title":"Stem Cells for the Improvement of Erectile and Cardiac Function in Aging Men","brief_summary":"Men who present with erectile dysfunction as defined as an IIEF (International Index of Erectile Function) score less than 21 will be evaluated for risk factors for cardiovascular disease (CVD). This is a single-blind study. Subjects will be randomized in a 2:1 fashion for treatment (ARM 1) versus placebo (ARM 2). Adipose tissue (fat) will be harvested from all patients and stem cells will be cultured. For those patients in the placebo arm the stem cells will be frozen for later use after one year when the patients cross over into the treatment arm.","overall_status":"Withdrawn","phases":["PHASE1"],"study_type":"INTERVENTIONAL","sponsor":"Baylor College of Medicine","enrollment":0,"countries":["United States"],"start_date":"2015-05-01","completion_date":"2022-02-01","last_update_date":"2015-05-25","source_url":"https://clinicaltrials.gov/study/NCT02107118","editorial_summary":"A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Withdrawn. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:40:48.95077+00:00","last_seen_at":"2026-09-25T06:05:08.502+00:00","metadata":{"sex":"MALE","acronym":null,"age_range":"40 Years","comparator":"ARM 1: AdMSC: adipose stem cells; ARM 2 Placebo","organization":"Baylor College of Medicine","interventions":["ARM 1: AdMSC: adipose stem cells","ARM 2: Placebo"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Improvements in IIEF scores of greater than 2 — 12 months","Improvements in RHI (reactive hyperemic index) scores of greater than 0.3 — 12 months"],"design_description":"RANDOMIZED · CROSSOVER · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Erectile Dysfunction","Cardiac Disease","ARM 1: AdMSC: adipose stem cells","ARM 2: Placebo"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: stem cell.","quality_checked_at":"2026-09-25T06:05:13.559725+00:00","duplicate_cluster_key":"id:nct02107118","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2015-05-01 to 2022-02-01","comparator":"ARM 1: AdMSC: adipose stem cells; ARM 2 Placebo","confidence":"structured-source","population":"MALE · 40 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:08.549Z","intervention":["ARM 1: AdMSC: adipose stem cells","ARM 2: Placebo"],"participants":0,"study_design":"RANDOMIZED · CROSSOVER · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE1","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Improvements in IIEF scores of greater than 2 — 12 months","Improvements in RHI (reactive hyperemic index) scores of greater than 0.3 — 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"stem-cells","is_published":true,"match_reasons":["Title contains controlled term: stem cell.","Abstract contains controlled term: stem cell.","Source terminology contains: stem cell.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Stem cells","slug":"stem-cells"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/50846","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}