{"type":"trials","record":{"id":53,"source_id":"clinicaltrials-gov","external_id":"NCT07723339","title":"BIOANCIENT_EX: Effects of a Physical Exercise Program in Centenarians of the BIOANCIENT Cohort: A Randomized Clinical Trial.","brief_summary":"This study aims to evaluate the effects of a home intervention of individualized multicomponent physical exercise program (including strength, balance, flexibility, and mobility training) on functional health, physical capacity, and biological markers in centenarians. The intervention includes periodic monitoring and individualized exercise progression every three weeks.","overall_status":"Enrolling By Invitation","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Fundacion Miguel Servet","enrollment":60,"countries":["Spain"],"start_date":"2026-08-13","completion_date":"2027-12-01","last_update_date":"2026-09-01","source_url":"https://clinicaltrials.gov/study/NCT07723339","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:44:59.105435+00:00","last_seen_at":"2026-09-16T06:17:41.106+00:00","metadata":{"acronym":"BIOANCIENT_EX","organization":"Fundacion Miguel Servet","source_has_results":false},"controlled_terms":["Aging","Cellular Senescence","Biomarkers / Blood","Exercise","Frailty"],"relevance_confidence":70,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: cellular senescence.","quality_checked_at":"2026-09-16T06:17:41.23623+00:00","duplicate_cluster_key":"id:nct07723339","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"senolytics","is_published":true,"match_reasons":["Source terminology contains: cellular senescence.","Title supplies longevity context: centenarian.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["controlled terminology","title context","study type"],"relevance_score":70,"intelligence_topics":{"name":"Senolytics","slug":"senolytics"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/53","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}