{"type":"trials","record":{"id":76,"source_id":"clinicaltrials-gov","external_id":"NCT07645001","title":"Therapeutic Synergy of Probiotic Augmented Conventional Antidiabetic Pharmacotherapy in Gestational Diabetes Mellitus","brief_summary":"1. To compare the effects of metformin, insulin, and their combination with multistrain probiotics on glycemic control and insulin resistance in women with gestational diabetes mellitus (GDM), assessed by FPG, HbA1c, fasting insulin, and HOMA-IR. 2. To compare the effects of metformin, insulin, and their combination with multistrain probiotics on inflammatory biomarkers in women with GDM. 3. To determine the effect of multistrain probiotic supplementation alongside standard therapy on maternal and neonatal outcomes, including gestational age at delivery, mode of delivery, birth weight, Apgar score, and NICU admission.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Riphah International University","enrollment":200,"countries":["Pakistan"],"start_date":"2026-07-29","completion_date":"2027-06-01","last_update_date":"2026-07-30","source_url":"https://clinicaltrials.gov/study/NCT07645001","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:44:59.105435+00:00","last_seen_at":"2026-09-16T06:17:42.144+00:00","metadata":{"acronym":null,"organization":"Riphah International University","source_has_results":false},"controlled_terms":["Gestational Diabetes","GRP 1 Tab metformin","GRP 2 Inj insulin","GRP 3 Tab metformin + HI flora sachet","GRP 4 Inj insulin + HI flora sachet"],"relevance_confidence":90,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Abstract contains controlled term: metformin.","quality_checked_at":"2026-09-16T06:17:42.274423+00:00","duplicate_cluster_key":"id:nct07645001","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"metformin","is_published":true,"match_reasons":["Abstract contains controlled term: metformin.","Source terminology contains: metformin.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["abstract","controlled terminology","study type"],"relevance_score":90,"intelligence_topics":{"name":"Metformin","slug":"metformin"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/76","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}