{"type":"trials","record":{"id":86186,"source_id":"isrctn","external_id":"ISRCTN31223043","title":"Effects of a combined exercise programme on physical fitness, heart-rate regulation and continued physical activity in older adults","brief_summary":"The overall objective was to examine the effects of a supervised multicomponent training programme on physical fitness, internal training load, cardiac autonomic modulation and physical activity adherence in functionally autonomous older adults, and to examine the subsequent evolution of these outcomes during supervised maintenance or programme cessation.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Universidad Autónoma de Nuevo León","enrollment":60,"countries":["Mexico"],"start_date":"2018-08-13","completion_date":"2019-09-27","last_update_date":"2026-08-18","source_url":"https://www.isrctn.com/ISRCTN31223043","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:47:37.046+00:00","metadata":{"sex":"All","age_range":"Mixed","comparator":null,"attribution":"Source: ISRCTN ISRCTN31223043; retrieved 2026-09-25","interventions":["Behavioural"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":[],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Healthy ageing, including physical fitness, functional performance, cardiometabolic health, cardiac autonomic modulatio…","The study comprises two consecutive phases. Recruitment begins on 4 June 2018 through advertisements, leaflets, notices…","Behavioural"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: exercise, physical activity.","quality_checked_at":"2026-09-25T03:47:40.623255+00:00","duplicate_cluster_key":"id:isrctn31223043","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2018-08-13 to 2019-09-27","comparator":null,"confidence":"structured-source","population":"All · Mixed","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:47:37.047Z","intervention":["Behavioural"],"participants":60,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":[],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise, physical activity.","Abstract contains controlled term: physical activity.","Title supplies longevity context: older adult.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86186","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}