{"type":"trials","record":{"id":86221,"source_id":"isrctn","external_id":"ISRCTN11572715","title":"Frailty and sarcopenia experience in persons with Parkinson's disease","brief_summary":"Current study objectives as of 17/02/2026: Overall study aim: 1. To examine the prevalence, clinical correlates, and lived experience of frailty and sarcopenia in persons with PD (PwP), and to integrate these findings to inform conceptual understanding and future clinical assessment. This overarching aim will be achieved through the following study objectives: 1. To map how frailty and sarcopenia are conceptualised and measured in PD research. 2. To determine the prevalence of frailty and sarcopenia in PwP in Ireland. 3. To examine the differences in clinical, functional, and disease-related characteristics between frail/sarcopenic and robust PwP. 4. To explore the lived experiences PwP living with frailty and sarcopenia. 5. To integrate quantitative and qualitative findings to examine alignment and divergence between clinical constructs and lived experience Previous study objectives: The prevalence of frailty and sarcopenia is higher in persons with Parkinson's disease (PwP) in Ireland compared to the general population (11% prevalence of frailty in those >55 years, and 8.1% prevalence of confirmed sarcopenia among older adults, as per the literature). Study aims: 1. Identify the…","overall_status":"Recruiting","phases":[],"study_type":"Observational","sponsor":"Royal College of Surgeons in Ireland","enrollment":0,"countries":["Ireland"],"start_date":"2025-06-01","completion_date":"2027-07-11","last_update_date":"2026-02-17","source_url":"https://www.isrctn.com/ISRCTN11572715","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:45:57.257+00:00","metadata":{"sex":"All","age_range":"Mixed","comparator":null,"attribution":"Source: ISRCTN ISRCTN11572715; retrieved 2026-09-25","interventions":["Mixed"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Current primary outcomes as of 17/02/2026: The prevalence of frailty (measured using the fried frailty phenotype, frail…","Current secondary outcomes as of 17/02/2026: 1. The conceptual overlap in domains identified in validated tools used in…"],"design_description":"Observational","source_has_results":false},"controlled_terms":["Parkinson's disease","Current methodology as of 17/02/2026: This will be a cross-sectional study, aiming to identify the prevalence of sarcop…","Participant information sheet","Mixed"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T03:45:57.562724+00:00","duplicate_cluster_key":"id:isrctn11572715","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-06-01 to 2027-07-11","comparator":null,"confidence":"structured-source","population":"All · Mixed","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:57.260Z","intervention":["Mixed"],"participants":0,"study_design":"Observational","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Current primary outcomes as of 17/02/2026: The prevalence of frailty (measured using the fried frailty phenotype, frail…","Current secondary outcomes as of 17/02/2026: 1. The conceptual overlap in domains identified in validated tools used in…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as Observational."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as Observational."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86221","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}