{"type":"trials","record":{"id":86278,"source_id":"isrctn","external_id":"ISRCTN30405954","title":"Evaluating mobility and strength training with and without protein supplements in pre-frail/frail older adults with low protein intake","brief_summary":"The aim of this multicentre, parallel, two-group, randomized controlled feasibility study is to find out if it is possible to carry out a larger trial comparing exercise plus extra protein to exercise alone, in older people with low protein intake. The study will find out if we can find enough people with a low protein diet willing to take part; whether participants are happy to take the protein supplements; and whether NHS physiotherapy departments can provide the exercise sessions.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"University of Oxford","enrollment":20,"countries":["United Kingdom","England"],"start_date":"2022-11-01","completion_date":"2024-07-31","last_update_date":"2026-01-08","source_url":"https://www.isrctn.com/ISRCTN30405954","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:47:37.046+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN30405954; retrieved 2026-09-25","interventions":["Mixed"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Feasibility will be assessed taking into account the following and using pre-defined stop/go criteria: 1. Recruitment r…","A secondary aim of the study is to trial the data collection procedures to be used in a main trial. We will collect the…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Pre-frail/frail older adults with low protein intake","A multicentre, parallel, two-group, randomized controlled feasibility trial conducted in NHS community and secondary ca…","Mixed"],"relevance_confidence":80,"source_quality_score":98,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: strength training.","quality_checked_at":"2026-09-25T03:47:40.623255+00:00","duplicate_cluster_key":"id:isrctn30405954","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-11-01 to 2024-07-31","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:47:37.057Z","intervention":["Mixed"],"participants":20,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Feasibility will be assessed taking into account the following and using pre-defined stop/go criteria: 1. Recruitment r…","A secondary aim of the study is to trial the data collection procedures to be used in a main trial. We will collect the…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: strength training.","Title supplies longevity context: frail, older adult.","Study type is explicitly identified as Interventional."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86278","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}