{"type":"trials","record":{"id":86308,"source_id":"isrctn","external_id":"ISRCTN47660107","title":"Training Grandma/pa against frailty","brief_summary":"Frail and pre-frail elders undergoing the physical exercise programmes will improve in frailty level, physical performance, and quality of life as compared with frail and pre-frail elders undergoing lifestyle education. Exercising and healthy lifestyle habit developed through a 6-month coaching programme is sustained at 12 months after the active intervention period.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"University of Hong Kong","enrollment":390,"countries":["Hong Kong"],"start_date":"2016-01-01","completion_date":"2018-06-30","last_update_date":"2021-12-22","source_url":"https://www.isrctn.com/ISRCTN47660107","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:47:37.046+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN47660107; retrieved 2026-09-25","interventions":["Behavioural"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Measured at baseline, T1 (6 months), T2 (12 months), and T3 (18 months): 1. Frailty score is measured by the FRAIL scal…","Measured at baseline, T1 (6 months), T2 (12 months), and T3 (18 months): 1. Other physical performance measures (e.g.,…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Exercise training program (including aerobic exercise, resistance exercise and healthy lifestyle education) in prefrail…","There are three arms for the intervention. They are aerobic exercise, resistance exercise, and healthy lifestyle educat…","Participant information sheet","Protocol file","Behavioural"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T03:47:40.623255+00:00","duplicate_cluster_key":"id:isrctn47660107","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-01-01 to 2018-06-30","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:47:37.059Z","intervention":["Behavioural"],"participants":390,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Measured at baseline, T1 (6 months), T2 (12 months), and T3 (18 months): 1. Frailty score is measured by the FRAIL scal…","Measured at baseline, T1 (6 months), T2 (12 months), and T3 (18 months): 1. Other physical performance measures (e.g.,…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86308","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}