{"type":"trials","record":{"id":86342,"source_id":"isrctn","external_id":"ISRCTN75362861","title":"Does nut consumption decrease biological age and improve cardiovascular risk factors? Are cashews better than almonds?","brief_summary":"The researchers hypothesized that a regular intake of nuts within a standardized diet is capable of improving several parameters of cardiometabolic risk including: anthropometric, blood pressure and biochemical, as well as in the pattern of DNA methylation as a biological indicator of cellular aging, compared to a control group. Additionally, they hypothesized that according to the nut consumed (almonds or cashew nuts), the improvements in certain parameters will be more specific.","overall_status":"Suspended","phases":[],"study_type":"Interventional","sponsor":"University of Valencia","enrollment":80,"countries":["Spain"],"start_date":"2019-12-27","completion_date":"2021-06-30","last_update_date":"2020-04-17","source_url":"https://www.isrctn.com/ISRCTN75362861","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Suspended. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:46:00.774+00:00","metadata":{"sex":"All","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN75362861; retrieved 2026-09-25","interventions":["Mixed"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["All the outcome measures will be measured at baseline and after 2 months. In addition, for the primary outcomes and for…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Cardiometabolic risk and aging","Participants will be randomized into three groups (1:1:2) by simple random assignment through a computer program. There…","Mixed"],"relevance_confidence":80,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: biological age.","quality_checked_at":"2026-09-25T03:46:01.039122+00:00","duplicate_cluster_key":"id:isrctn75362861","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-12-27 to 2021-06-30","comparator":null,"confidence":"structured-source","population":"All · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:00.776Z","intervention":["Mixed"],"participants":80,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["All the outcome measures will be measured at baseline and after 2 months. In addition, for the primary outcomes and for…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"biological-age-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: biological age.","Title supplies longevity context: biological age.","Study type is explicitly identified as Interventional."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Biological age biomarkers","slug":"biological-age-biomarkers"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86342","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}