{"type":"trials","record":{"id":86444,"source_id":"isrctn","external_id":"ISRCTN70130279","title":"Effects of the six-month training on cognitive, physical performance, and daily physical activity in older adults","brief_summary":"Study part A (cognition and gait): Combined physical and cognitive training (strength, balance, and virtual-reality video-game dancing) interventions can increase cognitive function (particularly attention) and gait parameters (particularly dual task cost of walking) to a greater extent than combined physical and cognitive training (strength, balance, and walking with memory tasks) and physical training alone (aerobic exercise, strength, and balance). Study part B (aerobic performance and executive function): Combined physical (aerobic exercise, strength, and balance) and cognitive training components, can increase measures of aerobic endurance performance [particularly heart rate variability (HRV) and heart rate recovery] to a greater extent than physical training (aerobic exercise, strength, and balance) alone. There is an association between HRV and executive function. Study part C (prevention of falls and one year follow up): Combined physical and cognitive training interventions, can decrease anxiety of falling and fall frequency to a greater extent than physical training (including aerobic exercise, strength, and balance) alone. One year after the six-month training interven…","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Swiss Federal Institute of Technology Zurich (ETH) (Switzerland)","enrollment":90,"countries":["Switzerland"],"start_date":"2012-09-03","completion_date":"2014-04-30","last_update_date":"2015-07-10","source_url":"https://www.isrctn.com/ISRCTN70130279","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:45:34.377+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN70130279; retrieved 2026-09-25","interventions":["Behavioural"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["1. Study part A (cognition and gait): 1.1 Test battery for cognitive function 1.2 Test for attention and concentration:…","1. Study part A (cognition and gait): 1.1. Gait parameters are assessed with the GAITRite system (CIR Systems, USA). Th…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Geriatrics related conditions of independent living and community dwelling in old adults","Participants follow a six months guided training intervention. Training sessions take place twice weekly for one hour e…","Behavioural"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: physical activity.","quality_checked_at":"2026-09-25T03:45:36.517565+00:00","duplicate_cluster_key":"id:isrctn70130279","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2012-09-03 to 2014-04-30","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:34.536Z","intervention":["Behavioural"],"participants":90,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["1. Study part A (cognition and gait): 1.1 Test battery for cognitive function 1.2 Test for attention and concentration:…","1. Study part A (cognition and gait): 1.1. Gait parameters are assessed with the GAITRite system (CIR Systems, USA). Th…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: physical activity.","Abstract contains controlled term: exercise.","Title supplies longevity context: older adult.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86444","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}