{"type":"trials","record":{"id":86461,"source_id":"isrctn","external_id":"ISRCTN31767087","title":"A high-intensity functional exercise program for older people with dementia and living in residential care facilities (The Umeå Dementia and Exercise Study – The UMDEX Study)","brief_summary":"1. A high-intensity functional exercise program will reduce dependence in personal activities of daily living (ADL). 2. The high-intensity functional exercise program will reduce falls, especially among people able to independently rise up from a chair, and improve physical (balance, mobility) and cognitive functions. 3. The exercise program will have a positive effect on depressive symptoms, psychological wellbeing, and behaviour and psychological symptoms of dementia (BPSD). 4. The exercise program is applicable, perceived as positive by the participants, and will not have a negative impact on mortality, diseases, or hospital admissions. 5. High levels of parathyroid hormone (PTH) and low levels of vitamin D will decrease the effect of the exercise program on ADL, falls, and physical and cognitive functions.","overall_status":"Completed","phases":["Not Applicable"],"study_type":"Interventional","sponsor":"Umeå University (Sweden)","enrollment":183,"countries":["Sweden"],"start_date":"2011-08-29","completion_date":"2013-02-02","last_update_date":"2019-02-20","source_url":"https://www.isrctn.com/ISRCTN31767087","editorial_summary":"A registered Not Applicable study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:34.939462+00:00","last_seen_at":"2026-09-25T03:45:34.377+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN31767087; retrieved 2026-09-25","interventions":["Other"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Dependence in personal activities of daily living (ADL) using the Functional Independence Measurement (FIM) and the Bar…","1. Balance using Berg Balance Scale (BBS), at 4 and 7 months, respectively. 2. Mobility using self-paced timed walk (fo…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Dementia disorders","Exercise intervention: The exercise intervention is based on the High-Intensity Functional Exercise Program (the HIFE P…","results","1 results","Other"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: exercise.","quality_checked_at":"2026-09-25T03:45:36.517565+00:00","duplicate_cluster_key":"id:isrctn31767087","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2011-08-29 to 2013-02-02","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:34.544Z","intervention":["Other"],"participants":183,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Not Applicable","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Dependence in personal activities of daily living (ADL) using the Functional Independence Measurement (FIM) and the Bar…","1. Balance using Berg Balance Scale (BBS), at 4 and 7 months, respectively. 2. Mobility using self-paced timed walk (fo…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: older people.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86461","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}