{"type":"trials","record":{"id":86488,"source_id":"isrctn","external_id":"ISRCTN62134200","title":"How changing HIV treatment affects sleep, mood, quality of life and health in people around or after the menopause and older adults living with HIV","brief_summary":null,"overall_status":"Recruiting","phases":[],"study_type":"Observational","sponsor":"University of Sussex","enrollment":0,"countries":["United Kingdom","England","Wales"],"start_date":"2026-06-08","completion_date":"2027-08-08","last_update_date":"2026-08-05","source_url":"https://www.isrctn.com/ISRCTN62134200","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:38.915204+00:00","last_seen_at":"2026-09-25T03:45:55.344+00:00","metadata":{"sex":"All","age_range":"Mixed","comparator":null,"attribution":"Source: ISRCTN ISRCTN62134200; retrieved 2026-09-25","interventions":["Not Specified"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":[],"design_description":"Observational","source_has_results":false},"controlled_terms":["Experiences of adults in the peri/post-menopausal period or aged ≥60 years switching HIV treatment","This is a multi-centre, mixed-methods observational study conducted at UK NHS HIV treatment centres, incorporating both…","Protocol file","Not Specified"],"relevance_confidence":80,"source_quality_score":98,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sleep.","quality_checked_at":"2026-09-25T03:45:56.411056+00:00","duplicate_cluster_key":"id:isrctn62134200","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-06-08 to 2027-08-08","comparator":null,"confidence":"structured-source","population":"All · Mixed","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:55.346Z","intervention":["Not Specified"],"participants":0,"study_design":"Observational","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":[],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: sleep.","Title supplies longevity context: older adult.","Study type is explicitly identified as Observational."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86488","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}