{"type":"trials","record":{"id":86580,"source_id":"isrctn","external_id":"ISRCTN55452501","title":"Illumination in human aging: sleep and mood effects","brief_summary":"Bright white light would reduce depression and improve sleep disorders related to circadian rhythm disturbance.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"National Institutes of Health (NIH)/National Institute of Aging (NIA) (USA)","enrollment":81,"countries":["United States of America"],"start_date":"2000-04-01","completion_date":"2004-01-31","last_update_date":"2008-02-14","source_url":"https://www.isrctn.com/ISRCTN55452501","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:38.915204+00:00","last_seen_at":"2026-09-25T03:45:38.816+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN55452501; retrieved 2026-09-25","interventions":["Other"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["1. Mood scales 2. Light recording 3. Wrist actigraphy 4. Assays of urine for aMT6s 5. Assays of saliva for melatonin","No secondary outcome measures"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Depression and disturbed sleep","One hour bright white light compared to one hour dim red light at three different times of day.","Results","Other"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: sleep.","quality_checked_at":"2026-09-25T03:45:39.558477+00:00","duplicate_cluster_key":"id:isrctn55452501","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2000-04-01 to 2004-01-31","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:38.874Z","intervention":["Other"],"participants":81,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["1. Mood scales 2. Light recording 3. Wrist actigraphy 4. Assays of urine for aMT6s 5. Assays of saliva for melatonin","No secondary outcome measures"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: sleep.","Abstract contains controlled term: sleep, circadian.","Source terminology contains: sleep.","Title supplies longevity context: aging.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86580","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}