{"type":"trials","record":{"id":86581,"source_id":"isrctn","external_id":"ISRCTN69400161","title":"Illumination in Human Aging: Sleep and Mood Effects","brief_summary":"Bright green light would reduce depression and improve sleep disorders related to circadian rhythm disturbance.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"National Institutes of Health, National Institute of Aging (NIH, NIA) (USA)","enrollment":33,"countries":["United States of America"],"start_date":"2004-02-01","completion_date":"2005-01-31","last_update_date":"2011-08-16","source_url":"https://www.isrctn.com/ISRCTN69400161","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:38.915204+00:00","last_seen_at":"2026-09-25T03:45:38.816+00:00","metadata":{"sex":"Not Specified","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN69400161; retrieved 2026-09-25","interventions":["Other"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Mood scales, light recording, and wrist actigraphy","Not provided at time of registration"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Depression and sleep disturbance","One hour of bright green light treatment compared to one hour of dim red light treatment given within one hour of wakin…","results","Other"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: sleep.","quality_checked_at":"2026-09-25T03:45:39.558477+00:00","duplicate_cluster_key":"id:isrctn69400161","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2004-02-01 to 2005-01-31","comparator":null,"confidence":"structured-source","population":"Not Specified · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:38.874Z","intervention":["Other"],"participants":33,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Mood scales, light recording, and wrist actigraphy","Not provided at time of registration"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: sleep.","Abstract contains controlled term: sleep, circadian.","Source terminology contains: sleep.","Title supplies longevity context: aging.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86581","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}