{"type":"trials","record":{"id":86589,"source_id":"isrctn","external_id":"ISRCTN17134958","title":"Comparison of the effect of pure fat injection vs injection of enriched fat with stem cells in repairing age-related changes on the face","brief_summary":"The effect of pure autologous fat grafting with adipose tissue-derived stem cells-enriched autologous fat grafting on repairing age-related changes 6 months after injection is different.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Islamic Azad Medical Sciences University, Mashhad branch","enrollment":72,"countries":["Iran"],"start_date":"2014-03-21","completion_date":"2016-09-21","last_update_date":"2022-08-31","source_url":"https://www.isrctn.com/ISRCTN17134958","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:41.482264+00:00","last_seen_at":"2026-09-25T03:45:41.453+00:00","metadata":{"sex":"Female","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN17134958; retrieved 2026-09-25","interventions":["Procedure/Surgery"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Difference between the two groups in terms of the effect of pure autologous fat grafting vs adipose tissue-derived stem…","Age and patient demographic information evaluated using a demographic questionnaire at baseline"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Facial fat injection due to aging changes","This quasi-randomized clinical trial study was performed on 72 women aged 20-60 years old who applied for fat transplan…","Procedure/Surgery"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: stem cell.","quality_checked_at":"2026-09-25T03:45:41.678571+00:00","duplicate_cluster_key":"id:isrctn17134958","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2014-03-21 to 2016-09-21","comparator":null,"confidence":"structured-source","population":"Female · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:45:41.455Z","intervention":["Procedure/Surgery"],"participants":72,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Difference between the two groups in terms of the effect of pure autologous fat grafting vs adipose tissue-derived stem…","Age and patient demographic information evaluated using a demographic questionnaire at baseline"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"stem-cells","is_published":true,"match_reasons":["Title contains controlled term: stem cell.","Abstract contains controlled term: stem cell.","Title supplies longevity context: age-related.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Stem cells","slug":"stem-cells"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86589","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}