{"type":"trials","record":{"id":86752,"source_id":"isrctn","external_id":"ISRCTN11241011","title":"FINE-ST: Frailty and inequality in stroke","brief_summary":"Frailty, co-morbidity and health inequality negatively impact stroke outcomes. Understanding the relationship between frailty, multi-morbidity, inequality and outcome will inform the design of trials for current and future health care interventions in an ageing stroke population.","overall_status":"Completed","phases":[],"study_type":"Observational","sponsor":"University of Nottingham","enrollment":207,"countries":["United Kingdom","England"],"start_date":"2020-09-17","completion_date":"2021-12-31","last_update_date":"2026-04-01","source_url":"https://www.isrctn.com/ISRCTN11241011","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:45:55.470179+00:00","last_seen_at":"2026-09-25T04:04:16.009+00:00","metadata":{"sex":"All","age_range":"Mixed","comparator":null,"attribution":"Source: ISRCTN ISRCTN11241011; retrieved 2026-09-25","interventions":["Other"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["1. Frailty will be measured using the CFS, PRISMA 7 and FI-GCA at baseline and day 90. 2. Functional outcome will be me…","1. Frailty will be measured using the CFS, PRISMA 7 and FI-GCA at baseline and day 90. 2. Disability will be measured u…"],"design_description":"Observational","source_has_results":false},"controlled_terms":["To initiate a stroke cohort to inform the relationship between frailty, multi-morbidity, socioeconomic status and clini…","The study simply collects information through administration of a questionnaire at two time points (baseline and 90 day…","Protocol file","Other"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T04:04:25.705398+00:00","duplicate_cluster_key":"id:isrctn11241011","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2020-09-17 to 2021-12-31","comparator":null,"confidence":"structured-source","population":"All · Mixed","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T04:04:16.076Z","intervention":["Other"],"participants":207,"study_design":"Observational","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["1. Frailty will be measured using the CFS, PRISMA 7 and FI-GCA at baseline and day 90. 2. Functional outcome will be me…","1. Frailty will be measured using the CFS, PRISMA 7 and FI-GCA at baseline and day 90. 2. Disability will be measured u…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as Observational."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/86752","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}