{"type":"trials","record":{"id":87,"source_id":"clinicaltrials-gov","external_id":"NCT07707297","title":"BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)","brief_summary":"Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100. Centenarians represent a unique biological model of extreme longevity, often exhibiting delayed onset of age-related diseases and preserved functional capacity. This study aims to establish an intergenerational cohort of centenarians in Navarra (Spain) to investigate the biological, clinical, environmental, and lifestyle factors associated with extreme longevity. By integrating multidimensional data-including clinical assessments, functional and cognitive measures, and biological markers-this study seeks to improve understanding of aging mechanisms and identify potential determinants of healthy aging.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Fundacion Miguel Servet","enrollment":333,"countries":["Spain"],"start_date":"2026-02-04","completion_date":"2027-12-31","last_update_date":"2026-07-16","source_url":"https://clinicaltrials.gov/study/NCT07707297","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:44:59.105435+00:00","last_seen_at":"2026-09-16T06:17:42.144+00:00","metadata":{"acronym":"BIOANCIENT","organization":"Fundacion Miguel Servet","source_has_results":false},"controlled_terms":["Aging","Cellular Senescence","Biomarkers / Blood","Age-Related Diseases","Frailty"],"relevance_confidence":70,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: cellular senescence.","quality_checked_at":"2026-09-16T06:17:42.274423+00:00","duplicate_cluster_key":"id:nct07707297","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"senolytics","is_published":true,"match_reasons":["Source terminology contains: cellular senescence.","Title supplies longevity context: centenarian.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["controlled terminology","title context","study type"],"relevance_score":70,"intelligence_topics":{"name":"Senolytics","slug":"senolytics"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/87","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}