{"type":"trials","record":{"id":87119,"source_id":"isrctn","external_id":"ISRCTN18313457","title":"A study looking at the accuracy of using optical coherence tomography angiography at diagnosing an eye condition called neovascular age-related macular degeneration to see if it is just as good as fluorescein angiography","brief_summary":"ATHENA is a study to see if optical coherence tomography angiography (OCTA) used alongside optical coherence tomography (OCT) is just as good at diagnosing neovascular age-related macular degeneration (nAMD) as the OCT scan used with fluorescein angiography (FA).","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Moorfields Eye Hospital NHS Foundation Trust","enrollment":1067,"countries":["United Kingdom","England"],"start_date":"2022-01-10","completion_date":"2023-10-31","last_update_date":"2024-06-03","source_url":"https://www.isrctn.com/ISRCTN18313457","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"All","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN18313457; retrieved 2026-09-25","interventions":["Other"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["The sensitivity and specificity of the index tests, OCTA combined with OCT and FA combined with OCT, for the detection…","1. The sensitivity and specificity of the index tests, OCTA alone and FA alone, for the detection of nAMD in participan…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Neovascular age-related macular degeneration (nAMD)","Patients presenting to secondary care with suspected nAMD will undergo an OCT. If nAMD is clinically suspected followin…","Study website","Other"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn18313457","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-01-10 to 2023-10-31","comparator":null,"confidence":"structured-source","population":"All · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.567Z","intervention":["Other"],"participants":1067,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["The sensitivity and specificity of the index tests, OCTA combined with OCT and FA combined with OCT, for the detection…","1. The sensitivity and specificity of the index tests, OCTA alone and FA alone, for the detection of nAMD in participan…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87119","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}