{"type":"trials","record":{"id":87130,"source_id":"isrctn","external_id":"ISRCTN45308629","title":"Effects of lutein and omega-3 fat enriched egg consumption on visual function in older adults: Implications for age-related macular degeneration","brief_summary":"Lutein and DHA enriched egg consumption will improve retina function in Caucasian older adults by increasing egg-nutrient associated blood profiles while not adversely affecting plasma lipid profiles. More specifically, in Caucasian older adults, lutein and DHA enriched egg consumption will: 1. Improve self-assessed health and vision status 2. Improve electrophysiological retina function 3. Not influence TC and TAG concentrations 4. Not influence HDL-C/LDL-C particle size 5. Increase DHA in plasma and erythrocytes 6. Increase lutein in plasma","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"University of Manitoba","enrollment":30,"countries":["Canada"],"start_date":"2013-07-01","completion_date":"2014-09-01","last_update_date":"2018-06-27","source_url":"https://www.isrctn.com/ISRCTN45308629","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN45308629; retrieved 2026-09-25","interventions":["Supplement"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["1. Self-assessed health and vision status measured using a modified version of the National Eye Institute Visual Functi…","1. Average dietary intake, measured using a 3-day food record analyzed using The Food Processor software between DURING…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["General health of the retina and prevention of age-related macular degeneration","Avoidance of retina/eye related food items for one month prior and throughout the duration of the trial (6 weeks) inclu…","Supplement"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn45308629","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2013-07-01 to 2014-09-01","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.572Z","intervention":["Supplement"],"participants":30,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["1. Self-assessed health and vision status measured using a modified version of the National Eye Institute Visual Functi…","1. Average dietary intake, measured using a 3-day food record analyzed using The Food Processor software between DURING…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related, older adult.","Study type is explicitly identified as Interventional."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87130","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}