{"type":"trials","record":{"id":87139,"source_id":"isrctn","external_id":"ISRCTN30128134","title":"Imaging immune cells in the human eye using Indocyanine-Green dye","brief_summary":"The aim of this study is to evaluate the feasibility of using intravenous ICG dye to image immune cells within the eyes of patients.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"University of Bristol","enrollment":12,"countries":["United Kingdom","England"],"start_date":"2017-05-08","completion_date":"2017-12-01","last_update_date":"2020-02-26","source_url":"https://www.isrctn.com/ISRCTN30128134","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"All","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN30128134; retrieved 2026-09-25","interventions":["Mixed"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Visualisation of ICG cell labelling in the eyes of patients with diseases affecting the eye, based upon retinal photogr…","1. The optimum time after ICG injection for cells to be seen 2. Absence of ICG cell signals in control eyes without dis…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Known ocular diseases including neovascular age-related macular degeneration, posterior uveitis and central serous reti…","The first 12 patients will undergo ICG angiography as already clinically required by their treating physician. Addition…","results","Mixed"],"relevance_confidence":70,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn30128134","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2017-05-08 to 2017-12-01","comparator":null,"confidence":"structured-source","population":"All · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.576Z","intervention":["Mixed"],"participants":12,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Visualisation of ICG cell labelling in the eyes of patients with diseases affecting the eye, based upon retinal photogr…","1. The optimum time after ICG injection for cells to be seen 2. Absence of ICG cell signals in control eyes without dis…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Title supplies longevity context: aging.","Study type is explicitly identified as Interventional."],"matched_fields":["controlled terminology","title context","study type"],"relevance_score":70,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87139","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}