{"type":"trials","record":{"id":87143,"source_id":"isrctn","external_id":"ISRCTN17604865","title":"Effect of Lutemax 2020 on visual and brain health markers","brief_summary":"This study is to see the effect of Lutemax 2020 (L/Zi) at 10 and 20 mg over placebo on visual and brain health markers. Lutein supplementation studies have demonstrated an increase in macular pigment optical density (MPOD) and this study will show relationship of increase in MPOD may have an effect on brain health markers. This study also may provide us the dose effect on visual and brain health markers.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"OmniActive Health Technologies Inc","enrollment":60,"countries":["United States of America"],"start_date":"2014-10-06","completion_date":"2016-06-05","last_update_date":"2018-07-31","source_url":"https://www.isrctn.com/ISRCTN17604865","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"All","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN17604865; retrieved 2026-09-25","interventions":["Supplement"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["1. Macular Pigment Density (MPOD), assessed via heterochromatic flicker photometry 2. Contrast sensitivity (at 8 cycles…","1 Cognitive function using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) 2. Overall af…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Age-related macular degeneration","This is a double blind placebo controlled trial having three arm parallel study. Subjects were randomized by blocks and…","results","Supplement"],"relevance_confidence":60,"source_quality_score":98,"freshness_score":50,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn17604865","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2014-10-06 to 2016-06-05","comparator":null,"confidence":"structured-source","population":"All · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.578Z","intervention":["Supplement"],"participants":60,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["1. Macular Pigment Density (MPOD), assessed via heterochromatic flicker photometry 2. Contrast sensitivity (at 8 cycles…","1 Cognitive function using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) 2. Overall af…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as Interventional."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87143","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}